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2、作时并不存在颅外动脉扩张(kuzhng),仅有轻度的颅内动脉扩张(kuzhng)。提示未来有关偏头痛的研究应关注于外周和中枢性疼痛通路而非单纯的动脉扩张。,第二页,共三十四页。,概念(ginin),1983年Woolf首次提出外伤(wishng)后疼痛的中枢敏感化的概念,用来描述中枢神经系统在生理或解剖上任何增强基底敏感性、疼痛感知、神经兴奋性的变化。,头痛:因重复(chngf)或长时间的疼痛刺激,外周炎症或神经受损,使中枢神经系统的痛觉通路尤其是三叉神经尾核、脊髓背角感觉神经元等产生一种长期的可逆的兴奋性增高,兴奋阈值降低,突触效能增加的现象。,Woolf CJ.Evidence for a
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