1、Chapter 11 The Skin Skin:Epidermis、Dermis一、Histological structure of skin 一Keratinizing and layers of Epidermis:A stratified squamous epithelium which consists of keratinocytes and other types of cells(Melanocyte、Merkels cell、Langerhans cell)。,第一页,共三十一页。,第二页,共三十一页。,Five layers of epidermis and kerat
2、inization:1、Stratum Basale2、Stratum Spinosum3、Stratum Granulosum4、Stratum Lucidum5、Stratum Corneum,第三页,共三十一页。,1、The Stratum Basale:a single layer of columnar or high cuboidal cells.2、The Stratum Spinosum:410 layers of cells which become irregularly polygonal with moderate flattening parallel to the
3、surface.nucleus is distinguishable only in a few cells(keratohyalin、tonofilament),第四页,共三十一页。,3、The Stratum Granulosum:It consists of 23 layers of flattened rhomboid cells whose cytoplasm contains numerous keratohyalin granules.4、The Stratum Lucidum:23 layers of flattened and densely packed cells.The
4、 nuclei and the outline of the structures are disappear.,第五页,共三十一页。,5、The Stratum Corneum:layers of flattened、cornified cells without nuclei(horny cells)and filled with keratin.二Unkeratinocyte(Melanocyte、Merkels cell、Langerhans cell),第六页,共三十一页。,第七页,共三十一页。,二、Dermis:consists of connective tissue掌握1、Th
5、e Papillary Layer:loose connective tissue.Dermal papillae、tactile corpuscle2、The Reticular Layer:more dense and contains coarse collagenous fibers.There are some little structures such as hair follicle、sebaceous glands and sweat glands in this layer.,第八页,共三十一页。,第九页,共三十一页。,三、Accessory glands of skin.
6、熟悉 1、Hair:hair shaft、hair root、hair follicle、hair bulb、hair papilla(毛乳头)、arrector pilimuscle.2、Sebaceous gland 3、Sweat gland:scrine sweat gland 小apocrine sweat gland 大,毛囊,第十页,共三十一页。,Chapter 14 Digestive system一、Generation struction 一Mucosa:1、Epithelium2、Lamina propria3、Muscularis mucosae,第十一页,共三十一页。
7、,二Submucosa三Muscularis四Adventitia,第十二页,共三十一页。,三、Esophagus1.Mucosa(15.9)1).strat.squam.nonkerat.epith.2).lamina propria.3).mascularies2.Submucosa 1.esophageal glands mucus secreting,第十三页,共三十一页。,C.Muscularis 1.proximal third:skeletal 2.middle third:mixed 3.distal third:smoothD.Adventitia/Serosa,第十四页,共
8、三十一页。,IV.Stomach,A.Gross Anatomy 1.cardiac region 2.fundus 3.body 4.pyloric region 5.rugae a.mucosa&submucosa,第十五页,共三十一页。,一.Mucosa 1.surface epithelium a.simple columnar,第十六页,共三十一页。,2.lamina propria a.gastric pitsb.gastric glands(branched tubular)1)chief cells 2)parietal cells 3)mucous neck cells 4)
9、Stem cells:mitotic 5)Endocrine cell,第十七页,共三十一页。,Parietal(oxyntic)cells a)pyramidal b)spherical nucleus c)eosinophilic d)mitochondria e)intracellular canaliculus f)microvilli g)secrete HCl,intrinsic factor,第十八页,共三十一页。,parietal(oxyntic)cells,resting,active,第十九页,共三十一页。,Zymogenic cells a)rER/basophilic
10、b)synthesize pepsinogen,第二十页,共三十一页。,二Submucosa 三Muscularis and Serosa 1.three layers of smooth muscle fibers,第二十一页,共三十一页。,V.Small Intestine,Gross Anatomy 1.regions a.duodenum b.jejunum c.ileum 2.plicae circulares a.mucosa b.submucosa,第二十二页,共三十一页。,3.villi(15.20,15.27)a.epithelium b.lamina propria,第二十
11、三页,共三十一页。,一.Mucosa epithelium:intestinal villussmall interstinal gland 1.simple columnar 1)absorptive cells brush border(mv)2)goblet cells,第二十四页,共三十一页。,3)Paneths cells a)eosinophilic,apical secretory granules b)antibacterial 4)enteroendocrine cells5)stem cells,第二十五页,共三十一页。,第二十六页,共三十一页。,2.Lamina prop
12、ria a.glands b.capillaries c.lacteals d.smooth muscle fibers e.loose CT f.lymphocytes g.WBCs,第二十七页,共三十一页。,(二)Submucosa(三Muscularis and Serosa,第二十八页,共三十一页。,VI.Large Intestine no folds no villi一Colon1、Mucosa2、Submucosa 3、Muscularis4.、Adventitia,第二十九页,共三十一页。,二 Appendix A.Similar to large intestine B.Numerous lymph nodules,第三十页,共三十一页。,内容总结,Chapter 11 The Skin。2).lamina propria.。3.villi(15.20,15.27)。3)Paneths cells。图14-28 小肠腺 示潘氏细胞(焰红与坚固绿染色)。(三Muscularis and Serosa。二 Appendix,第三十一页,共三十一页。,