1、 2018 1 2018 2019 04 2018 2 () 208,308,0 10 0.20 0 10 0 2018 3 .2 .5 .8 . 13 . 27 . 41 . 46 . 47 . 53 . 59 . 60 . 149 2018 4 DNA DNA GMP 2018 5 30254 ShanXi C&Y Pharmaceutical Group Co., LTD. C&Y Pharmaceutical 53 037010 53 037010 ww.cy- stockcy- 53 53 0352-6116426 0352-6116426 0352-6116452 0352-611
2、6452 stockcy- xyy1934 htp:/ 2018 6 61 7 2018 2017 2016 1,136,495,67.79 938,927,986.26 21.04% 746,076,863.59 7,241,080.6 21,673,419.09 -6.59% 30,147,707.56 -13,638,85.14 3,250,098.68 -519.64% 6,23,15.62 38,40,743.90 40,103,878.52 -4.15% 41,650,140.64 / 0.0348 0.1037 -6.4% 0.147 / 0.0348 0.1037 -6.4%
3、0.147 0.90% 2.67% -1.7% 3.79% 2018 2017 2016 1,495,710,196.93 1,518,593,270.43 -1.51% 1,432,590,079.66 79,091,85.14 819,585,507.27 -2.50% 808,65,182.37 270,50,94.29 270,03,86.19 281,871,58.82 314,119,198.49 7,317,083.24 10,089,769.04 4,40,358.17 -14,606,129.79 5,048,57.63 9,115,4.61 -3,595,234.48 -2
4、4,207,62.90 5,372,758.75 11,393,57.14 11,640,042.60 10,034,385.41 2018 7 1 2 2018 2017 2016 -35,57.31 20,256,217.89 12,813,056.20 26,019,809.37 7,273,603.81 4,457,718.53 319,980.3 7,914,328.28 15,740,184.15 -60,648.30 -3,893,143.84 3,761,857.65 4,327,953.71 3,80,756.41 1,281,70.64 8,79,732.02 5,295,
5、650.53 20,879,935.80 18,423,320.41 23,914,51.94 - 1 1 1 2018 8 1 AD 2 AD AD D3 DNA 3 1 2 2018 9 GMPGMP 3 DNA 4 5 20181,5232019612018 1 35.89% 56.30% 2018 10 32.72% 54.97% 697.70% 78.81% 69.60% 91.39% 2 1 DNA 1 3 1 G20830342 C4-10 0.6g/ 2018424 2 G20830343 C 1.0g/ 2018424 3 G2083034 C 1.0g/ 2018424 2
6、 1314 1 2360198 30 2028127 2 2803410 35 20281 20 3 2803453 5 202812 6 4 28041916 35 20281 20 5 23643828 35 2028413 6 2362878 42 202846 7 23628794 4 2028327 2018 11 8 2364162 41 202846 9 23628926 42 202846 10 23628301 4 202846 1 23643609 35 202846 12 2364072 41 202846 13 2364072 41 202846 14 23643894
7、 35 202846 15 23643586 41 2028413 16 23628978 42 202846 17 23643747 41 202846 18 23629019 42 2028327 2 3 GMPGMP 1 201603 * 20201231 2GMP GMP 2018 12 1 SX2018023 202343 2 ZJ2018045 2023419 3 ZJ2018046 2023419 4 SC2018054 2023813 4 11 1 1 ZL20171024697.0 2017414 20 3 ZL201730125287.5 20174 14 10 2 DHA
8、 ZL20171024697.0 2018119 10 2018 13 20184+720182018 1 2 20183 2018 1 1 3 4 GMPGMPGMP 5 2018 14 2018- 202030% 6 4S5S 2 1 4 2 3 CODPCOPD 3 3 4 1.1 5 3.1 6 BCR/ABL BCRABLBCR/ABL 7 ALK ALK 1 BE 2 3 4 BE 2018 15 5 / 6 1 2 1 2018 2017 1,136,495,67.79 10% 938,927,986.26 10% 21.04% 1,050,396,357.60 92.42% 7
9、29,840,475.23 7.73% 43.92% 37,879,257.35 3.3% 86,807,462.05 9.25% -56.36% 38,858,80.67 3.42% 43,08,981.24 4.58% -9.65% 2,078,14.85 0.18% 71,048,205.05 7.57% -97.08% 7,283,107.32 0.64% 8,2,862.69 0.8% -11.43% 529,567,728.16 46.60% 318,870,895.05 3.96% 6.08% 59,391,63.76 5.23% 48,041,854.54 5.12% 23.6
10、2% 138,547,98.91 12.19% 97,134,389.89 10.35% 42.64% 76,870,929.58 6.76% 70,454,486.65 7.50% 9.11% 8,402,402.85 0.74% 6,974,909.4 0.74% 20.47% 8,697,237.51 0.7% 6,594,718.76 0.70% 31.8% 183,746,472.21 16.17% 137,454,691.03 14.64% 3.68% 45,171,964.62 3.97% 4,314,529.87 4.72% 1.93% 37,879,257.35 3.3% 8
11、6,807,462.05 9.25% -56.36% 38,858,80.67 3.42% 43,08,981.24 4.58% -9.65% 2,078,14.85 0.18% 71,048,205.05 7.57% -97.08% 2018 16 7,283,107.32 0.64% 8,2,862.69 0.8% -11.43% 87,627,738.75 7.71% 70,636,14.16 7.52% 24.06% 202,076,018.01 17.78% 139,12,368.24 14.82% 45.25% 38,69,601.27 34.20% 341,241,698.50
12、36.34% 13.91% 75,45,693.74 6.64% 79,58,786.50 8.47% -5.17% 156,274,820.05 13.75% 111,017,026.75 11.82% 40.7% 38,646,623.19 3.40% 26,109,42.51 2.78% 48.02% 187,725,172.78 16.52% 148,324,62.16 15.80% 26.56% 2,917,897.4 2.4% -10.0% 2 10% 1,050,396,357.60 240,294,580.35 7.12% 43.92% 23.91% 3.69% 529,567
13、,728.16 103,909,08.83 80.38% 6.08% 27.76% 5.89% 138,547,98.91 11,142,728.90 91.96% 42.64% 54.97% -0.64% 183,746,472.21 38,949,571.59 78.80% 3.68% 9.64% 4.64% 202,076,018.01 54,950,07.68 72.81% 45.25% 34.90% 2.09% 38,69,601.27 95,804,272.07 75.35% 13.91% -5.95% 5.20% 156,274,820.05 35,245,892.72 7.45
14、% 40.7% 4.19% 7.92% 187,725,172.78 36,26,916.57 80.68% 26.56% -17.56% 10.34% 1 3 2018 2017 - 3,285.24 3,485.51 -5.75% 3,247.58 3,764.49 -13.73% 2018 17 682.6 724.49 -5.78% - / 96,192.65 89,202.3 7.84% / 8,31.85 9,934.65 -11.61% / 14,250.29 23,72.73 -39.93% - 265,608.13 254,250 4.47% 262,0 276,0 -5.0
15、7% 51,593.5 5,201.68 -6.54% - 237,583.54 189,53.17 25.35% 201,850.02 201,690.87 0.08% 46,564.15 79,323.91 -41.30% - / 1,673.9 3,565.15 -53.05% / 1,603.93 3,382.52 -52.58% / 59.68 143.32 -58.36% - 1,734.87 3,160.07 -45.10% 1,52.61 3,70.31 -58.85% 398.42 616.05 -35.3% 30% 139.93%2018GMP 241.30% 3 4 5
16、2018 2017 178,401,402.26 74.24% 151,438,852.35 7.92% -3.67% 12,632,575.07 5.26% 11,267,539.18 5.80% -0.54% 49,260,603.02 20.50% 31,656,380.48 16.29% 4.21% 240,294,580.35 10.0% 194,362,72.0 10.0% 0.0% 8,410,97.50 57.54% 15,203,808.79 60.95% -3.41% 2018 18 1,637,408.89 11.20% 2,918,270.39 11.70% -0.50
17、% 4,568,096.11 31.25% 6,820,901.78 27.35% 3.91% 14,616,482.50 10.0% 24,942,980.95 10.0% 0.0% 2,842,981.40 58.31% 3,186,623.21 57.58% 0.74% 1,112,039.21 2.81% 1,327,53.31 23.9% -1.18% 920,425.79 18.8% 1,020,460.0 18.4% 0.4% 4,875,46.40 10.0% 5,534,616.51 10.0% 0.0% 6 20183 7 8 109,169,641.74 9.61% 0.
18、0% 5 1 1 28,370,658.8 2.50% 2 2 23,918,983.24 2.10% 3 3 21,34,789.78 1.8% 4 4 17,859,901.19 1.57% 5 5 17,685,308.65 1.56% - 109,169,641.74 9.61% 89,98,730.64 45.38% 0.0% 5 2018 19 1 1 25,284,0.0 12.75% 2 2 19,52,758.60 9.86% 3 3 17,98,48.25 9.08% 4 4 13,907,09.63 7.01% 5 5 13,246,514.16 6.68% - 89,9
19、8,730.64 45.38% 3 2018 2017 624,560,614.74 429,160,121.90 45.53% 120,506,361.07 117,804,287.39 2.29% 13,29,854.83 12,801,861.71 3.34% 53,540,68.37 43,4,656.49 23.24% 4 7,01.8954.45%6.17%1,657.8323.64% 2018 2017 2016 282 278 267 16.94% 15.93% 14.09% 70,118,942.07 45,398,642.06 38,416,576.09 6.17% 4.8
20、4% 5.15% 16,578,273.70 1,953,985.57 4,621,945.4 23.64% 4.30% 12.03% 28.95% 9.02% 15.30% 2018 20 5 2018 2017 1,217,973,652.86 87,140,79.53 37.29% 1,179,532,908.96 847,036,921.01 39.25% 38,40,743.90 40,103,878.52 -4.15% 12,807,917.38 179,915,208.53 -92.8% 35,970,026.06 184,305,392.67 -80.48% -23,162,1
21、08.68 -4,390,184.14 -427.59% 353,80,0.0 216,70,0.0 63.27% 370,010,286.06 262,138,420.78 41.15% -16,210,286.06 -45,438,420.78 64.32% -931,650.84 -9,724,726.40 90.42% 1 2 3,84.07976.925,06.07 -2,868,282.13 -19.42% 50,60,718.51 342.92% 31,510,924.37 213.29% 2018 21 1,935,512.04 13.10% 1 2018 2017 147,6
22、85,348.50 9.87% 151,496,79.34 9.98% -0.11% 261,82,323.81 17.50% 237,29,874.03 15.62% 1.8% 130,924,492.08 8.75% 128,379,593.18 8.45% 0.30% 86,689,093.56 5.80% 84,414,538.72 5.56% 0.24% 79,78,323.16 5.3% 82,646,605.29 5.4% -0.11% 318,435,19.47 21.29% 234,329,191.78 15.43% 5.86% 71,258,532.11 4.76% 163
23、,06,712.67 10.74% -5.98% 129,0,0.0 8.62% 135,0,0.0 8.89% -0.27% 127,60,0.0 8.53% 30,20,0.0 1.9% 6.54% 2 3 90,0.0 58,472,256.89 10,875,463.60 50,406,563.02 38,509,43.58 10% 92,60,0.0 80% 51,013,727.09 2018 2 1 56,404,530.91 113,536,596.70 -50.32% 2 27,8,00.0 10.0% 0.0 32,702,417.5 2018 04 26 2018-029
24、 - - 27,8,00.0 - - - - - 0.0 32,702,417.5 - - - 3 4 5 1 2 10% 2018 23 140 391,892,711.48 238,053,385.28 13,065,146.85 10,937,472.47 10,823,721.37 20 27,818,295.83 176,953,868.38 237,949,859.68 17,089,513.2 20,508,197.47 980 25,257,601.72 20,638,35.93 34,528,747.79 4,28,70.78 3,893,951.41 10 240,542,
25、519.67 62,3,270.56 681,64,818.38 14,803,965.79 32,702,417.5 10 103,803,241.8 84,683,26.07 92,362,537.70 -4,47,736.95 -4,358,258.59 2025 201920192019117 +2018 2018 24 20172017-20301020181,5232019612018 2019 2019 2019 1 OTC 2 2019 3 2019 2018 25 4 2019GMP20195S GMP 5 6 2019 1 GMP 2 3 4 5 2018 26 20152
26、018 6 1 2018 27 20184 2520172017201720,830.80100.51,041.5420186 20184 2018- 2020 10 0 10 0.20 10 0 208,308,0 4,16,160.0 0.0 4,16,160.0 149,37,946.81 10.0% 2018 28 20 2019 4 26 2018 208,308,0 10 0.20 3 12016 20162016201620,830.8010 0.501,041.54 22017 20172017201720,830.8010 0.501,041.54 32018 2018201
27、820,830.8010 0.20416.62 2018 4,16,160.0 7,241,080.6 57.54% 0.0 0.0% 4,16,160.0 57.54% 2017 10,415,40.0 21,673,419.09 48.06% 0.0 0.0% 10,415,40.0 48.06% 2016 10,415,40.0 30,147,707.56 34.5% 0.0 0.0% 10,415,40.0 34.5% 1 2018 29 2011 08 19 2011 08 19 2011 08 19 2018 30 2011 08 19 2011 08 19 2018 31 201
28、5 09 01 2018 9 3 () 2015 09 01 2018 9 3 2 2018 32 2018615 2018201815 1 287,187,6.49274,93,142.95 68,709,182.9285,41,150.85 0.000.0 475,219.651,523,451.28 0.00.0 0.00.0 0.000.0 2 53,540,68.3743,4,656.49 20183 10 12 3 2018 3 1 1,395.94 10.0% 2,0 201804 26 2018-032 htp:/winfo.co - - 1,395.94 - 2,0 - -
29、- - - 2018 4 25 2018 2018 2,0 2018 34 2 3 4 5 1 1 2 3 2 1 2018 35 2017 12 15 5,0 2017 12 15 5,0 2018 01 09 5,0 2018 04 12 5,0 2018 01 09 5,0 2018 12 12 5,0 2018 11 19 5,0 2018 11 30 5,0 B1 10,0 B2 10,0 B3 10,0 B4 10,0 A1+B1+C1 10,0 A2+B2+C2 10,0 A3+B3+C3 10,0 A4+B4+C4 10,0 A4+B4+C4 12.51% D 0 70%E 0
30、 50%F 0 D+E+F 0 2018 36 2 3 1 2 4 1 1 2 3 4 2018 37 2 1 2 3 / 1. 2. 3. 4. 5. 6. 7. 8. 9. 4 3 1 DW01 24.48mg/L 458mg/L 1.31/ 7 / 1 DW01 0.95mg/L 30mg/L 0.051/ 0.5/ 1 DW01 8.508mg/L 70 mg/L 0.457/ 1 DW010.29 mg/L 8 mg/L 0.016/ 2018 38 1 150m/20921 2 26/ 3 GB12348-2082 4 2 2032034 2010140261271013-0261
31、 PH PH () 15,01201819 22018112 3201825 2018 39 42018228 52018330 6GMP2018420 730%20182,02018426 82GMP2018427 201852 920172018516 20172018628 20172018426 2018516 2018629 10 GMP2018816 1 20152018932018830 12 201891 13 2018925 14 5,0220181 19 15 20181 30 201819 htp:/ 2018112 htp:/ 2018 2018131 htp:/ 20
32、18 2018426 htp:/ 30% 2018426 htp:/ GMP 2018427 htp:/ GMP 201852 htp:/ 2018 40 30% 2018531 htp:/ 2018723 htp:/ GMP 2018816 htp:/ 2018912 htp:/ 201810 12 htp:/ 20181 19 htp:/ 201812 10 htp:/ 2018 41 1 52,790,729 25.34% -6,371,383 -6,371,383 46,419,346 2.28% 3 52,790,729 25.34% -6,371,383 -6,371,383 46
33、,419,346 2.28% 5,487,635 2.63% -5,487,635 -5,487,635 0 0.0% 47,303,094 2.71% -83,748 -83,748 46,419,346 2.28% 15,517,271 74.6% 6,371,383 6,371,383 161,8,654 7.72% 1 15,517,271 74.6% 6,371,383 6,371,383 161,8,654 7.72% 208,308,0 10.0% 0 0 208,308,0 10.0% 1 25% 2 201520189 3 2 2018 42 18,606,157 0 0 1
34、8,606,157 25% 13,343,769 0 0 13,343,769 25% 10,07,826 0 0 10,07,826 25% 5,487,635 5,487,635 0 0 2018 9 3 2,25,192 563,798 0 1,691,394 25% 1,279,80 319,950 0 959,850 25% 1,036,80 0 0 1,036,80 25% 712,80 0 0 712,80 25% 60,750 0 0 60,750 25% 52,790,729 6,371,383 0 46,419,346 - - 1 2 3 1 2018 43 14,303
35、13,284 9 0 9 0 5% 10 1.91% 24,808,209 0 18,606,157 6,202,052 21,607,843 8.54% 17,791,692 0 13,343,769 4,47,923 1,3,913 6.41% 13,343,768 0 10,07,826 3,35,942 13,02,634 4.79% 9,984,0 +984,0 0 9,984,0 2.63% 5,487,635 0 0 5,487,635 2.18% 4,54,464 - 51,80 0 4,54,464 1.85% 3,858,240 - 984,0 0 3,858,240 1.
36、68% 3,503,716 0 0 3,503,716 1.49% 3,12,70 - 3,647,90 0 3,12,70 1.32% 2,752,680 0 2,752,680 10 4 3 26.86% 10 9,984,0 9,984,0 6,202,052 6,202,052 5,487,635 5,487,635 4,54,464 4,54,464 4,47,923 4,47,923 3,858,240 3,858,240 3,503,716 3,503,716 3,35,942 3,35,942 2018 4 3,12,70 3,12,70 2,752,680 2,752,680
37、 10 10 10 3 26.86% 5 10 10 10 10 2 206 7 2010 5 2010 6 2016 7 2016 7 205 3 2010 5 2010 6 2016 7 2013 6 2016 7 2016 7 205 3 2010 5 2010 6 2016 7 2018 3 3 2018 45 206 7 2010 5 2010 6 2016 7 2016 7 205 3 2010 5 2010 6 2016 7 2013 6 2016 7 2016 7 205 3 2010 5 2010 6 2016 7 2018 3 10 4 10% 5 2018 46 2018
38、 47 48 2010 06 01 2019 07 06 17,791,692 0 0 0 17,791,692 65 2010 06 01 2019 07 06 24,808,209 0 0 0 24,808,209 60 2015 03 06 2019 07 06 2,25,192 0 0 0 2,25,192 52 2012 01 05 2019 07 06 1,382,40 0 0 0 1,382,40 61 2016 07 07 2019 07 06 1,279,80 0 0 0 1,279,80 46 2016 07 07 2019 04 03 0 0 0 0 0 49 2016
39、07 07 2019 07 06 0 0 0 0 0 49 2016 07 07 2019 07 06 0 0 0 0 0 49 2016 07 07 2019 07 06 0 0 0 0 0 57 2016 07 07 2019 07 06 0 0 0 0 0 48 2010 06 01 2019 07 06 0 0 0 0 0 53 2013 06 01 2019 07 06 0 0 0 0 0 47 2016 07 07 2019 07 06 0 0 0 0 0 40 2016 07 07 2018 03 30 0 0 0 0 0 48 2018 03 01 2019 07 06 13,
40、343,768 0 0 0 13,343,768 42 2016 07 07 2018 09 10 0 0 0 0 0 56 2016 07 07 2019 07 06 0 0 0 0 0 36 2018 09 2 2019 07 06 0 0 0 0 0 46 2018 11 30 2019 07 06 0 0 0 0 0 - - - - - - 60,861,061 0 0 0 60,861,061 2018 48 2018 02 03 2018 03 30 2018 09 10 2019 04 03 1 197132053201052010620167201362016720167 19
41、5412 206720105201062016720167 1959202201520153201592018220182 196712 EMBA2053201052010620167201212016720167 19584207120105201062013531 2013920151 2014320167201672018220182 1973320210208820102201510 2016720194 1970920167 19701 20167 19701 20167 2 19628203120167 1971120532010520106 1962208201062017620
42、136 20177 2018 49 3 1972620126201432014420149201410 20159201510 20151 20151 20167 197010 20532010520124201412 20106201662010220182 196319822016720167 19828204920952096201052010520101201012 201612 201712018920189 19728201210 2013720137201312 20163201810 20181 208 08 01 2010 02 01 2016 03 01 2012 02 0
43、1 2017 12 20 20201220 2015 02 01 20210726 2018 12 01 20211201 2017 05 16 20200516 2010 08 01 2017 07 01 20200701 2019 01 01 2019 01 01 20220101 2018 50 2018512.7 48 60.21 65 12.19 60 64.02 52 57.81 61 28.98 46 49 5 49 5 49 5 57 4.46 48 11.6 53 2.71 47 58.03 40 16.05 48 36.11 42 3.17 56 4.46 36 7.84
44、2018 51 46 - - - - 512.7 - 1 521 1,14 1,65 1,707 42 57 58 282 50 18 1,65 58 469 532 606 1,65 2 3 2018 52 4 2018 53 10% 9 3 , 3 1 2018 54 2018 5 1 2017 41.79% 2018 05 16 2018 05 16 2018-040 2 1 12 1 11 0 0 1 12 1 11 0 0 0 12 1 11 0 0 0 2 3 2018 56 1 30% 2 20182018 3 4 2018 2018 57 1 2 2019 04 27 2019
45、 4 27 htp:/ 2018 10.0% 10.0% 12341234 111 1 1% 2 1% 1 1% 2 1% 1 0.5%2 0.5% 1 1.5%21.5%1 1% 1.5%2 1% 1.5%1 1% 2 1% 0 0 2018 58 0 0 2018 59 2018 60 2019 04 26 2019 ZA13168 201812 31 2018 201812 31 2018 201812 31 164,64,367.64 13 1 2 3 4 5 6 7 8 2018 61 9 10 20181,136,495,667.79201721.04% 31 1 2 3 4 5
46、6 2018 1 2018 62 2 3 4 5 6 1 2018 12 31 147,685,348.50 151,496,79.34 2018 63 287,187,6.49 274,93,142.95 25,365,342.68 37,703,268.92 261,82,323.81 237,29,874.03 18,107,824.96 11,685,045.09 28,408,179.14 3,465,317.02 130,924,492.08 128,379,593.18 2,548,936.4 2,826,758.08 634,862,47.61 602,786,635.6 79
47、,78,323.16 82,646,605.29 86,689,093.56 84,414,538.72 318,435,19.47 234,329,191.78 71,258,532.11 163,06,712.67 93,812,184.11 111,702,325.28 30,651,031.24 17,141,623.36 164,64,367.64 205,864,367.64 2,982,904.3 1,758,745.98 2018 64 12,207,363.70 10,59,139.05 368,750.0 4,283,385.0 860,847,749.32 915,806
48、,634.7 1,495,710,196.93 1,518,593,270.43 129,0,0.0 135,0,0.0 68,709,182.92 85,411,150.85 9,694,897.5 9,914,06.46 13,96,42.80 12,430,514.57 4,132,032.92 25,56,075.86 101,849,07.54 132,930,926.4 475,219.65 1,523,451.28 31,20,0.0 75,0,0.0 398,51,613.73 476,252,674.18 127,60,0.0 30,20,0.0 2018 65 1,0,0.
49、0 1,0,0.0 6,985,536.65 6,19,606.96 30,3,308.15 3,767,09.21 165,918,84.80 71,16,616.17 564,470,458.53 547,419,290.35 208,308,0.0 208,308,0.0 425,79,318.09 43,118,620.8 15,646,620.24 15,646,620.24 149,37,946.81 152,512,26.15 79,091,85.14 819,585,507.27 132,147,853.26 151,58,472.81 931,239,738.40 971,1
50、73,980.08 1,495,710,196.93 1,518,593,270.43 2 18,43,390.28 36,691,075.23 2018 6 91,092,697.20 47,986,819.94 37,874.60 4,869,823.96 90,754,82.60 43,116,95.98 5,910,237.38 3,391,641.4 2,691,251.59 2,308,942.4 63,045,925.49 65,648,086.28 1,93,74.57 672,349.92 183,107,246.51 156,698,915.25 734,29,04.39
51、748,907,149.07 80,81,976.86 80,956,013.16 71,258,532.11 79,716,610.64 15,135,784.42 16,854,274.81 18,019,429.10 11,116,494.94 1,516,582.84 364,417.15 951,101.60 601,958.6 247,650.0 92,062,411.32 938,764,568.43 1,105,169,657.83 1,095,463,483.68 30,0,0.0 2018 67 43,821,402.24 51,76,06.85 3,164,958.8 4
52、,810,64.23 3,687,456.47 5,456,123.23 6,111,296.34 979,47.43 179,95,707.80 159,90,538.62 201,959.03 154,024.75 25,0,0.0 65,0,0.0 261,740,821.73 318,02,820.36 90,0,0.0 1,0,0.0 1,0,0.0 1,91,546.46 2,656,078.89 92,91,546.46 3,656,078.89 354,732,368.19 321,658,89.25 208,308,0.0 208,308,0.0 497,473,808.05
53、 497,473,808.05 2018 68 15,646,620.24 15,646,620.24 29,08,861.35 52,376,156.14 750,437,289.64 73,804,584.43 1,105,169,657.83 1,095,463,483.68 3 1,136,495,67.79 938,927,986.26 1,136,495,67.79 938,927,986.26 1,151,235,751.85 928,787,463.21 267,75,38.71 289,780,042.15 20,962,145.62 14,36,312.35 624,560
54、,614.74 429,160,121.90 120,506,361.07 117,804,287.39 53,540,68.37 43,4,656.49 13,29,854.83 12,801,861.71 13,595,490.70 15,423,237.11 76,253.2 3,167,246.3 50,60,718.51 21,460,181.2 1,730,801.37 1,765,575.60 -2,868,282.13 -3,973,297.7 -2,868,282.13 -4,310,716.51 2018 69 - - 1,075,54.85 20,85,285.29 -1
55、4,802,09.97 28,818,086.17 31,510,924.37 13,546,956.98 1,935,512.04 1,091,086.63 14,73,402.36 41,273,956.52 5,04,24.04 10,379,470.25 9,769,158.32 30,894,486.27 9,769,158.32 30,894,486.27 7,241,080.6 21,673,419.09 2,528,07.6 9,21,067.18 -130,19.2 -67,202.71 1. 2. -67,202.71 1. 2. 3. 2018 70 4. 5. -67,
56、202.71 6. -62,96.51 9,769,158.32 30,764,287.05 7,241,080.6 21,606,216.38 2,528,07.6 9,158,070.67 0.0348 0.1037 0.0348 0.1037 4 252,932,804.23 254,761,818.47 140,515,404.97 115,078,080.52 3,468,821.13 2,9,250.50 15,624,148.07 5,532,217.20 46,143,989.60 54,732,279.46 25,729,827.15 11,921,230.85 14,165
57、,945.36 13,463,709.56 14,21,074.12 8,424,47.92 92,535.57 540,983.42 4,159,38.60 10,025,930.12 81,231.13 150,0.0 23,303,85.32 10,034,412.93 -1,296,14.68 -965,587.07 2018 71 - 943,396.20 -12,546,18.0 1,193,532.19 642,59.06 1,419,382.16 937,427.70 -13,965,570.16 898,703.5 -1,013,675.37 2,026,601.52 -12
58、,951,894.79 -1,127,897.97 -12,951,894.79 -1,127,897.97 1. 2. 1. 2. 3. 4. 5. 6. -12,951,894.79 -1,127,897.97 -0.062 -0.054 -0.062 -0.054 2018 72 5 1,186,203,911.33 85,649,605.51 31,769,741.53 31,491,194.02 1,217,973,652.86 87,140,79.53 208,63,969.47 19,029,13.87 170,706,494.43 173,352,935.65 164,813,
59、617.34 118,957,897.43 635,348,827.72 35,696,954.06 1,179,532,908.96 847,036,921.01 38,40,743.90 40,103,878.52 2018 73 38,0,0.0 214,085.57 11,531,435.50 32,219,62.96 1,276,481.8 7,350,0.0 102,131,50.0 12,807,917.38 179,915,208.53 29,589,632.64 101,071,026.30 6,380,393.42 83,234,36.37 35,970,026.06 18
60、4,305,392.67 -23,162,108.68 -4,390,184.14 1,50,0.0 1,50,0.0 353,80,0.0 215,20,0.0 353,80,0.0 216,70,0.0 306,20,0.0 23,0,0.0 35,92,286.06 32,813,230.65 8,0,0.0 27,8,0.0 6,325,190.13 370,010,286.06 262,138,420.78 -16,210,286.06 -45,438,420.78 -931,650.84 -9,724,726.40 2018 74 148,526,9.34 158,251,725.
61、74 147,595,348.50 148,526,9.34 6 219,648,417.53 248,156,581.64 410,836.56 3,061,648.42 20,059,254.09 251,218,230.06 106,747,235.40 76,931,167.4 47,81,901.4 62,309,573.75 19,682,32.12 2,462,918.24 42,42,21.64 69,083,391.9 216,73,680.60 230,787,051.42 3,325,573.49 20,431,178.64 9,0,0.0 12,061,680.8 3,
62、907,052.40 908,759.50 130,0.0 102,831,50.0 12,970,40.38 115,868,52.40 16,198,52.97 31,73,236.35 27,8,0.0 1,525,190.13 70,70,0.0 4,086,52.97 103,98,426.48 -31,116,112.59 11,870,125.92 2018 75 115,0,0.0 50,0,0.0 45,90,0.0 8,972,627.10 160,90,0.0 138,972,627.10 95,0,0.0 95,0,0.0 19,57,365.85 23,274,508
63、.47 3,90,0.0 59,80,0.0 148,47,365.85 178,074,508.47 12,42,634.15 -39,101,81.37 -15,367,904.95 -6,80,576.81 3,801,295.23 40,601,872.04 18,43,390.28 3,801,295.23 7 208,308,0.0 43,118,620.8 15,646,620.24 152,512,26.15 151,58,472.81 971,173,980.08 2018 76 208,308,0.0 43,118,620.8 15,646,620.24 152,512,2
64、6.15 151,58,472.81 971,173,980.08 -17,319,302.79 -3,174,319.34 -19,40,619.5 -39,934,241.68 7,241,080.6 2,528,07.6 9,769,158.32 -17,319,302.79 -10,568,697.21 -27,8,0.0 1 2 3 4 -17,319,302.79 -10,568,697.21 -27,8,0.0 -10,415,40.0 -11,40,0.0 -21,815,40.0 1 2 3 -10,415,40.0 -11,40,0.0 -21,815,40.0 4 1 2
65、 3 4 5 2018 7 1 2 208,308,0.0 425,79,318.09 15,646,620.24 149,37,946.81 132,147,853.26 931,239,738.40 208,308,0.0 43,379,112.36 67,202.71 15,646,620.24 141,254,247.06 146,195,10.79 954,850,283.16 208,308,0.0 43,379,112.36 67,202.71 15,646,620.24 141,254,247.06 146,195,10.79 954,850,283.16 -260,491.4
66、8 -67,202.71 11,258,019.09 5,393,372.02 16,323,696.92 -67,202.71 21,673,419.09 9,158,070.67 30,764,287.05 -260,491.48 235,301.35 -25,190.13 1 1,50,00.0 1,50,00.0 2 2018 78 3 4 -260,491.48 -1,264,698.65 -1,525,190.13 -10,415,40.0 -4,0,0.0 -14,415,40.0 1 2 3 -10,415,40.0 -4,0,0.0 -14,415,40.0 4 1 2 3
67、4 5 1 2 208,308,0.0 43,118,620.8 15,646,620.24 152,512,26.15 151,58,472.81 971,173,980.08 8 2018 79 208,308,0.0 497,473,808.05 15,646,620.24 52,376,156.14 73,804,584.43 208,308,0.0 497,473,808.05 15,646,620.24 52,376,156.14 73,804,584.43 -23,367,294.79 -23,367,294.79 -12,951,894.79 -12,951,894.79 1
68、2 3 4 -10,415,40.0 -10,415,40.0 1 2 -10,415,40.0 -10,415,40.0 3 1 2 2018 80 3 4 5 1 2 208,308,0.0 497,473,808.05 15,646,620.24 29,08,861.35 750,437,289.64 208,308,0.0 497,473,808.05 15,646,620.24 63,919,454.11 785,347,882.40 208,308,0.0 497,473,808.05 15,646,620.24 63,919,454.11 785,347,882.40 -11,5
69、43,297.97 -11,543,297.97 -1,127,897.97 -1,127,897.97 1 2 2018 81 3 4 -10,415,40.0 -10,415,40.0 1 2 -10,415,40.0 -10,415,40.0 3 1 2 3 4 5 1 2 208,308,0.0 497,473,808.05 15,646,620.24 52,376,156.14 73,804,584.43 201069140207012753X2018 20553(C&Y PHARMACEUTICAL INVESTMENT HOLDINGS LIMITIED205128 205006
70、 1,402,0205323 0202 2018 82 20661,01,030.4920 06 6(2006)0730720661,030.49 2066206620637518,0206720678,0()()()()( 20612 20717070.7420071(20070506070820721,731.23 20764038.5420775,0244,850.172077(200703003120776,969.94 20710 20710 207371.2 120710 20710 2,0721,984.72071 200704720711 18,954.71 20831,045
71、.292084208220842008(014)20851 20912 610%11.4 620912 2010120103201012010120102,14020402021() % 1 24,0,0.0 24.0 2018 83 2 18,0,0.0 18.0 3 18,0,0.0 18.0 4 16,0,0.0 16.0 5 12,0,0.0 12.0 6 12,0,0.0 12.0 10,0,0.0 10.0 20102626 635.83%26 11.5 35.83%64.17%2010225 2010226 20104 % 1 15,40,80.0 15.408 2 13,0,0
72、.0 13.0 3 1,50,60.0 1.506 4 1,50,60.0 1.506 5 10,267,20.0 10.2672 6 7,70,40.0 7.704 7 7,70,40.0 7.704 8 3,0,0.0 3.0 9 2,50,0.0 2.50 10 2,0,0.0 2.0 1 1,60,0.0 1.60 12 1,580,0.0 1.580 13 1,40,0.0 1.40 14 1,30,0.0 1.30 15 1,080,0.0 1.080 16 1,050,0.0 1.050 17 1,0,0.0 1.0 18 1,0,0.0 1.0 19 14 5,320,0.0
73、5.320 10,0,0.0 10.0 2010516 2010430 2010430 15,464,427.2510,0,0.0015,464,427.25 2010430 201024365 2018 84 2010201183,380113.020181 201)1325413,80,013,800,0.0 201432 2014919 201410 22014201514051,303115.4252015872015)14781173,590,0.00173,590,00.0 201510 2208,308,0.0208,308,0.0 201812 31 20,830.8020,8
74、30.8053 53 2019426 201812 31 1 15 2 12 2018 85 1 2 1112 31 3 12 4 5 6 1 2 2018 86 1 2 2018 87 3 4 7 1 2 3 4 5 8 9 10 1 2 1 2 2018 8 3 4 5 3 1 2 1 2 4 5 2018 89 6 1 2 11 1 2 1 2 1 1 5.0% 12 30.0% 23 50.0% 3 10.0% 2018 90 2 3 12 1 2 3 4 5 1 2 13 1 2 2018 91 14 1 2 1 2 3 1 2 2018 92 3 15 16 1 12 2018 9
75、3 2 20 -70 10% 1.29%-4.50% 10 10% 9.0% 5 10% 18.0% 5 10% 18.0% 5 10% 18.0% 10 10% 9.0% 3 3.3% 17 18 1 1 2 3 2 2018 94 3 3 4 19 1 1 1 2 2 493-60 120 60 60 84 67 60 120 26 204 2018 95 3 2 1 2 1 2 3 4 5 20 21 1 2018 96 2 22 1 2 3 23 1 1 2 3 2 24 1 1 2018 97 2 2 25 1 2 3 1 2 26 / 2018 98 27 1 1 2 28 1 2
76、 3 29 1 2018 6 15 2018201815 2018615 2018201815 1 287,187,6.49274,93,142.95 68,709,182.9285,41,150.85 0.000.0 475,219.651,523,451.28 0.00.0 2018 9 0.00.0 0.000.0 2 53,540,68.3743,4,656.49 2 1 3% 5% 6% 10%11%16%17% 7% 15%25% 15% 15% 25% 15% 15% 25% 25% 25% 25% 25% 15% 2 12016201815% 22018 2018 10 201
77、815% 32017201815% 42017201815% 515%201815% 3 1 26,746.27 20,489.21 147,578,602.23 148,506,510.13 80,0.0 2,969,780.0 147,685,348.50 151,496,79.34 2,89,780.0 80,0.0 80,0.0 10,0.0 90,0.0 2,969,780.0 2 25,365,342.68 37,703,268.92 261,82,323.81 237,29,874.03 287,187,6.49 274,93,142.95 2018 101 1 1) 25,36
78、5,342.68 37,703,268.92 25,365,342.68 37,703,268.92 2) 0.0 3) 37,363,370.7 37,363,370.7 4) 0.0 0.0 2 1) 2018 102 28,187,34.31 9.03% 26,365,010.50 9.15% 261,82,323.81 256,706,672.48 9.4% 19,476,798.45 7.59% 237,29,874.03 2,83,022.21 0.97% 2,83,022.21 10.0% 1,48,612.14 0.56% 1,48,612.14 10.0% 291,020,3
79、56.52 10.0% 29,198,032.71 261,82,323.81 258,15,284.62 10.0% 20,925,410.59 237,29,874.03 1 1 251,21,56.65 12,561,078.32 5.0% 1 2 28,10,456.2 8,430,136.87 30.0% 2 3 6,983,032.27 3,491,516.14 50.0% 3 1,82,279.17 1,82,279.17 10.0% 28,187,34.31 26,365,010.50 % 1,217,612.14 1,217,612.14 10.0 386,878.18 38
80、6,878.18 10.0 376,30.36 376,30.36 10.0 231,0.0 231,0.0 10.0 17,030.0 17,030.0 10.0 148,83.0 148,83.0 10.0 126,178.08 126,178.08 10.0 2018 103 84,959.45 84,959.45 10.0 76,205.0 76,205.0 10.0 7,946.0 7,946.0 10.0 2,83,02.21 2,83,02.21 2) 8,279,590.24 0.0 3) 6,968.12 4) (%) 1,365,281.40 3.91 568,264.07
81、 9,514,274.56 3.27 475,713.73 8,56,612.80 2.94 428,30.64 6,404,684.80 2.20 320,234.24 6,26,560.0 2.14 31,328.0 42,07,413.56 14.46 2,103,870.68 3 1 1 16,679,262.03 92.11% 9,54,591.19 81.69% 2018 104 1 2 56,281.05 0.31% 1,459,680.35 12.49% 2 3 1,218,92.60 6.73% 637,076.49 5.45% 3 153,289.28 0.85% 43,6
82、97.06 0.37% 18,107,824.96 - 11,685,045.09 - 1 2 (%) 3,13,848.05 17.31 1,278,04.73 7.06 1,217,312.0 6.72 1,0,0.0 5.52 923,760.67 5.10 7,52,925.45 41.71 4 28,408,179.14 3,465,317.02 28,408,179.14 3,465,317.02 1 1) 1,046,400.0 3.40% 79,20.0 76.38% 247,20.00 1,598,40.0 4.5% 79,20.00 50.0% 79,20.0 28,160
83、,979.14 91.5% 28,160,979.14 32,6,117.02 92.8% 32,6,117.02 1,52,625.05% 1,52,6210.0% 905,2862.57% 905,286.210.0% 2018 105 6.20 6.20 .25 5 30,760,005.34 10.0% 2,351,826.20 28,408,179.14 35,169,803.27 10.0% 1,704,486.25 3,465,317.02 1,046,40.0 79,20.0 76.38% 1,046,40.0 79,20.0 - - % 1,209,693.65 1,209,
84、693.65 10.0 342,932.5 342,932.5 10.0 1,52,626.20 1,52,626.20 2) 647,39.95 0.0 3) 4) 2018 106 2,196,705.45 2,148,369.09 6,569,90.84 4,659,80.35 1,120,327.27 1,786,647.5 1,306,840.0 1,389,32.5 1,606,389.91 8,658,654.60 12,411,098.4 9,982,923.92 9,982,923.92 642,070.71 1,267,654.01 20,0.0 30,760,05.34
85、35,169,803.27 5) 9,982,923.92 1-2 32.45% 8,658,654.60 1 28.15% 2,0,0.0 1 6.50% 1,046,40.0 3 3.40% 79,20.0 950,854.14 1 2-3 3.09% - 2,638,832.6 - 73.59% 79,20.0 5 1 2018 107 35,498,283.95 1,352,314.97 34,145,968.96 37,78,319.68 1,117,784.78 36,670,534.90 6,415,741.24 6,415,741.24 1,256,074.34 1,256,0
86、74.34 71,816,35.50 278,683.12 71,537,672.40 75,614,905.91 174,298.18 75,40,607.73 821,93.81 821,93.81 814,763.93 814,763.93 45,641.01 45,641.01 169,965.19 169,965.19 376,506.12 376,506.12 4,932.18 4,932.18 17,463,874.24 17,463,874.24 13,739,869.21 13,739,869.21 132,5,490.17 1,630,98.09 130,924,492.0
87、8 129,671,676.14 1,292,082.96 128,379,593.18 2 1,117,784.78 234,530.19 1,352,314.97 174,298.18 29,258.13 194,873.19 278,683.12 1,292,082.96 53,78.32 194,873.19 1,630,98.09 3 4 6 2018 108 19,696,196.68 1,625,963.07 2,852,739.76 1,20,795.01 2,548,936.4 2,826,758.08 7 53,797,164.26 -1,296,144.68 52,501
88、,019.58 28,849,41.03 -1,572,137.45 27,27,303.58 82,646,605.29 -2,868,282.13 79,78,323.16 82,646,605.29 -2,868,282.13 79,78,323.16 8 1 1. 94,2,60.0 94,2,60.0 2. 4,90,0.0 4,90,0.0 1 2 4,90,0.0 4,90,0.0 2018 109 3 3. 1 2 4. 9,12,60.0 9,12,60.0 1. 9,808,061.28 9,808,061.28 2. 2,625,45.16 2,625,45.16 1 2
89、,230,972.68 2,230,972.68 394,472.48 394,472.48 3. 1 2 4. 12,43,506.4 12,43,506.4 1. 2. 1 3 1 2 4. 1. 86,689,093.56 86,689,093.56 2. 84,414,538.72 84,414,538.72 2 2018 110 3 201812 31 9 318,435,19.47 234,329,191.78 318,435,19.47 234,329,191.78 1 1. 169,536,845.6 94,238,305.35 49,530,937.21 12,424,014
90、.01 8,790,928.49 48,194,825.56 86,201.94 382,802,058.2 2. 5,117,037.72 42,456,063.56 20,56,921.41 1,32,48.38 1,585,478.96 10,602,074.26 1,857,040.21 13,507,064.50 1 1,526,539.96 7,392,362.36 1,140,507.16 209,947.31 2,938,018.48 13,207,375.27 2 5,117,037.72 40,929,523.60 13,174,59.05 181,941.2 1,375,
91、531.65 7,64,05.78 1,857,040.21 120,29,689.23 3 3. 17,454,473.15 4,34,07.06 1,81,40.98 1,039,20.00 209,7.12 23,95.04 25,152,923.35 1 4,34,07.06 1,81,40.98 1,039,20.00 209,7.12 23,95.04 7,698,450.20 12,54,473.15 12,54,473.15 4,90,0.00 4,90,0.0 2018 111 4. 207,19,410.23 132,360,291.85 68,216,417.64 12,
92、707,262.39 10,16,630.33 58,562,94.78 1,943,242.15 491,156,19.37 1. 51,110,205.85 39,567,015.53 23,201,489.81 8,349,471.81 4,758,08.79 21,451,501.25 35,093.40 148,472,86.4 2. 9,743,58.09 9,95,793.93 7,845,085.99 1,156,617.72 1,198,986.18 4,789,7.26 364,736.43 35,054,5.60 1 9,743,58.09 9,95,793.93 7,8
93、45,085.99 1,156,617.72 1,198,986.18 4,789,7.26 364,736.43 35,054,5.60 3. 4,864,018.27 3,019,737.51 1,607,801.06 93,596.0 189,578.45 191,690.85 10,806,42.14 1 3,019,737.51 1,607,801.06 93,596.0 189,578.45 191,690.85 5,942,403.87 4,469,545.79 4,469,545.79 394,472.48 394,472.48 4. 5,989,745.67 46,503,0
94、71.95 29,438,74.74 8,572,493.53 5,767,496.52 26,049,587.66 39,829.83 172,720,9.90 1. 2. 1 3. 1 4. 1. 151,209,64.56 85,857,219.90 38,7,642.90 4,134,768.86 4,39,13.81 32,513,357.12 1,543,412.32 318,435,19.47 2. 118,426,639.81 54,671,289.82 26,329,47.40 4,074,542.20 4,032,839.70 26,743,324.31 51,108.54
95、 234,329,191.78 2018 112 2 60,174,129.17 2010 7 21 2013 2 7 (B20130160 ) 2014 5 23 68 GMP 132,909.17 2012 3 2 (201256 ) 1,587,562.2 2018 113 10 71,258,532.11 163,06,712.67 71,258,532.11 163,06,712.67 1 70,54,832.11 70,54,832.11 70,54,832.11 70,54,832.11 82,210,968.40 82,210,968.40 1,139,13.63 1,139,
96、13.63 7,160,352.36 7,160,352.36 1,873,691.17 1,873,691.17 713,70.0 713,70.0 137,735.0 137,735.0 71,258,532.11 71,258,532.11 163,06,712.67 163,06,712.67 2 70,54,832.11 70,54,832.11 35% 82,210,968.40 10,736,654.80 92,947,623.20 10% 1,505,484.16 635,230.56 4.90% 2018 114 1,139,133.63 238,415.2 1,37,548
97、.85 10% 7,160,352.36 12,073,178.35 19,215,813.65 17,717.06 10% 1,873,691.17 52,257.80 2,425,948.97 10% 137,735.0 4,916,024.74 4,32,754.56 7,305.18 713,70.0 163,06,712.67 28,516,530.91 120,29,689.23 25,02.24 71,258,532.11 - - 1,505,484.16 635,230.56 - 11 1 5 1. 46,724,624.96 20,316,061.3 10,163,743.4
98、 11,30,00.0 45,940,00.0 11,09,00.0 12,548,00.0 12,280,00.0 39,980,00.0 210,351,429.73 2. 1,037,023.13 1,037,023.13 2018 115 1 1,037,023.13 1,037,023.13 2 3 3. 145,631.07 145,631.07 1 145,631.07 145,631.07 4. 46,724,624.96 20,316,061.3 11,05,135.50 11,30,00.0 45,940,00.0 11,09,00.0 12,548,00.0 12,280
99、,00.0 39,980,00.0 211,242,821.79 1. 5,062,789.30 20,316,061.3 5,351,353.27 6,072,743.53 39,37,142.96 9,111,119.42 7,547,13.0 1,565,098.04 4,245,63.60 98,649,104.45 2. 1,069,053.45 1,653,642.16 2,213,923.14 6,562,857.04 1,987,80.58 2,487,60.0 72,354.94 2,123,056.80 18,820,368.11 1 1,069,053.45 1,653,642.16 2,213,923.14 6,562,857.04 1,987,80.58 2,487,60.0 72,354.94 2,123,056.80 18,820,368.11 3. 38,834.8 38,834.8 1 38,834.8 38,834.8 4. 6,131,842.75 20,316,061.3 6,96,160.5 8,286,6.67 45,940,00.0 11,09,00.0 10,034,733.0 2,287,452.98 6,368,720.40 117,430,637.68 1.
