1、Designation:D759816(Reapproved 2017)Standard Test Method forDetermination of Thiodiglycol in Water by Single ReactionMonitoring Liquid Chromatography/Tandem MassSpectrometry1This standard is issued under the fixed designation D7598;the number immediately following the designation indicates the year
2、oforiginal adoption or,in the case of revision,the year of last revision.A number in parentheses indicates the year of last reapproval.Asuperscript epsilon()indicates an editorial change since the last revision or reapproval.1.Scope1.1 This procedure covers the determination of thiodiglycol(TDG)in s
3、urface water by direct injection using liquidchromatography(LC)and detected with tandem mass spec-trometry(MS/MS).TDG is qualitatively and quantitativelydetermined by this test method.This test method adheres tosingle reaction monitoring(SRM)mass spectrometry.1.2 This test method has been developed
4、by U.S.EPARegion 5 Chicago Regional Laboratory(CRL).1.3 The values stated in SI units are to be regarded asstandard.No other units of measurement are included in thisstandard.1.4 The detection verification level(DVL)and reportingrange for TDG are listed in Table 1.1.4.1 The DVL is required to be at
5、a concentration at least3 times below the reporting limit(RL)and have a signal/noiseratio greater than 3:1.Fig.1 displays the signal/noise ratio atthe DVL.1.4.2 The RL is the concentration of the Level 1 calibrationstandard as shown in Table 2.The reporting limit for this testmethod is 100 g/L.1.5 T
6、his standard does not purport to address all of thesafety concerns,if any,associated with its use.It is theresponsibility of the user of this standard to establish appro-priate safety and health practices and determine the applica-bility of regulatory limitations prior to use.1.6 This international
7、standard was developed in accor-dance with internationally recognized principles on standard-ization established in the Decision on Principles for theDevelopment of International Standards,Guides and Recom-mendations issued by the World Trade Organization TechnicalBarriers to Trade(TBT)Committee.2.R
8、eferenced Documents2.1 ASTM Standards:2D1129 Terminology Relating to WaterD1193 Specification for Reagent WaterD2777 Practice for Determination of Precision and Bias ofApplicable Test Methods of Committee D19 on WaterD3856 Guide for Management Systems in LaboratoriesEngaged in Analysis of WaterD3694
9、 Practices for Preparation of Sample Containers andfor Preservation of Organic ConstituentsD5847 Practice for Writing Quality Control Specificationsfor Standard Test Methods for Water AnalysisE2554 Practice for Estimating and Monitoring the Uncer-tainty of Test Results of a Test Method Using Control
10、Chart Techniques2.2 Other Documents:U.S.EPA publication SW-846 Test Methods for EvaluatingSolid Waste,Physical/Chemical Methods33.Terminology3.1 Definitions:3.1.1 For definitions of terms used in this standard,refer toTerminology D1129.3.2 Definitions of Terms Specific to This Standard:3.2.1 detecti
11、on verification level,DVL,na concentrationthat has a signal/noise ratio greater than 3:1 and is at least threetimes below the reporting limit(RL).3.2.2 independent reference material,IRM,na material ofknown purity and concentration obtained either from theNational Institute of Standards and Technolo
12、gy(NIST)or otherreputable supplier.The IRM shall be obtained from a differentlot of material than is used for calibration.1This test method is under the jurisdiction of ASTM Committee D19 on Waterand is the direct responsibility of Subcommittee D19.06 on Methods forAnalysis forOrganic Substances in
13、Water.Current edition approved June 15,2017.Published July 2017.Originallyapproved in 2009.Last previous edition approved in 2016 as D7598 16.DOI:10.1520/D7598-16R17.2For referenced ASTM standards,visit the ASTM website,www.astm.org,orcontact ASTM Customer Service at serviceastm.org.For Annual Book
14、of ASTMStandards volume information,refer to the standards Document Summary page onthe ASTM website.3Available from National Technical Information Service(NTIS),U.S.Depart-ment of Commerce,5285 Port Royal Road,Springfield,VA,22161 or at http:/www.epa.gov/epawaste/hazard/testmethods/index.htm.Copyrig
15、ht ASTM International,100 Barr Harbor Drive,PO Box C700,West Conshohocken,PA 19428-2959.United StatesThis international standard was developed in accordance with internationally recognized principles on standardization established in the Decision on Principles for theDevelopment of International Sta
16、ndards,Guides and Recommendations issued by the World Trade Organization Technical Barriers to Trade(TBT)Committee.1 3.3 Acronyms:3.3.1 CCC,nContinuing Calibration Check3.3.2 IC,nInitial Calibration3.3.3 LC,nLiquid Chromatography3.3.4 LCS/LCSD,nLaboratoryControlSample/Laboratory Control Sample Duplicate3.3.5 MDL,nMethod Detection Limit3.3.6 MeOH,nMethanol3.3.7 mM,nmillimolar,1 103moles/L3.3.8 MRM,nMultiple Reaction Monitoring3.3.9 MS/MSD,nMatrix Spike/Matrix Spike Duplicate3.3.10 NA,adjNot Avail