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Science 2018-06-01.pdf

1、CREDITS:(FROM TOP)C.BICKEL/SCIENCE;TNG COLLABORATION;HELIOVIS AG 1 JUNE 2018 VOL 360 ISSUE 6392 939SCIENCE sciencemag.org1 JUNE 2018 VOLUME 360 ISSUE 6392CONTENTS962Metabolic microenvironmentsaffect drug responsesNEWSIN BRIEF944 News at a glanceIN DEPTH 948 SCIENTISTS AIM TO SMOKE OUT WILDFIRE IMPAC

2、TSU.S.campaign to study how plumes affect human health and environment By W.Cornwall949 WILL U.S.ACADEMIES EXPEL SEXUAL HARASSERS?Prestigious bodies consider changing bylaws to eject members who offend By M.Wadman951 NEW COPIES OF OLD GENE DROVE BRAIN EXPANSIONResearch shows how genes supercharge ne

3、uron formation during human development By E.Pennisi952 EUROPES SCIENCE SPENDING SET FOR ANOTHER BIG BOOSTCommission seeks 97.6 billion for“Horizon Europe”By T.RabesandratanaINSIGHTSPERSPECTIVES 958 DECISION-MAKING IN A STORM OF DISCONTENTRegulation of pesticides such as glyphosate needs to include

4、societal assessment By N.M.van Straalen and J.Legler960 DUNES ACROSS THE SOLAR SYSTEMDespite a very thin atmosphere,dunes may form on Pluto By A.G.Hayes RESEARCH ARTICLE P.992962 THE NUTRIENT ENVIRONMENT AFFECTS THERAPYNutrient availability affects cancer cell metabolism and therapeutic responses By

5、 A.Muir and M.G.Vander Heiden964 ANCIENT HUMAN GENOMESKEYS TO UNDERSTANDING OUR PASTAncient genomes from different times and continents are helping to understand past human migrations By A.Achilli et al.REPORTS PP.1024&1028966 NEUROMORPHIC CIRCUITS IMPART A SENSE OF TOUCHFlexible organic transistors

6、 transmit force signals encoded for direct input to human neurons By C.Bartolozzi REPORT P.998967 A NEW VIEW OF EMBRYO DEVELOPMENT AND REGENERATIONTranscriptome atlases of vertebrate embryos and regeneration enrich our understanding of development By R.M.Harland RESEARCH ARTICLES PP.979,980,&981POLI

7、CY FORUM 969 STUDENT-CENTERED,MODERNIZED GRADUATE STEM EDUCATIONRebalance incentives to promote culture change By A.I.Leshner953 UNITED KINGDOM UNVEILS AMBITIOUS AIR POLLUTION PLANBid to slash particulate pollution draws praise and doubts By M.WarrenFEATURE 954 THE GALAXY BUILDERS Galaxy simulations

8、 are finally producing realistic resultsand surprising insights into the evolution of the universe By A.Cho954952DA_0601TOC.indd 9395/30/18 11:04 AMPublished by AAASon June 3,2018 http:/science.sciencemag.org/Downloaded from CREDITS:(FROM TOP)NASA/JOHNS HOPKINS UNIVERSITY APPLIED PHYSICS LABORATORY/

9、SOUTHWEST RESEARCH INSTITUTE/ZLDOYLE;MAURITIUS IMAGES GMBH/ALAMY STOCK PHOTO1 JUNE 2018 VOL 360 ISSUE 6392 941SCIENCE sciencemag.orgCONTENTS1 JUNE 2018 VOLUME 360 ISSUE 6392RESEARCHIN BRIEF 976 From Science and other journalsRESEARCH ARTICLES SINGLE-CELL ANALYSIS979 Single-cell reconstruction of dev

10、elopmental trajectories during zebrafish embryogenesis J.A.Farrell et al.RESEARCH ARTICLE SUMMARY;FOR FULL TEXT:dx.doi.org/10.1126/science.aar3131980 The dynamics of gene expression in vertebrate embryogenesis at single-cell resolution J.A.Briggs et al.RESEARCH ARTICLE SUMMARY;FOR FULL TEXT:dx.doi.o

11、rg/10.1126/science.aar5780981 Single-cell mapping of gene expression landscapes and lineage in the zebrafish embryo D.E.Wagner et al.PERSPECTIVE P.967987 SUSTAINABILITYReducing foods environmental impacts through producers and consumers J.Poore and T.Nemecek PODCAST992 PLANETARY SCIENCEDunes on Plut

12、o M.W.Telfer et al.PERSPECTIVE P.960REPORTS 998 BIOMATERIALSA bioinspired flexible organic artificial afferent nerve Y.Kim et al.PERSPECTIVE P.966;VIDEOINDUCED SEISMICITY1003 The November 2017 Mw 5.5 Pohang earthquake:A possible case of induced seismicity in South Korea F.Grigoli et al.1007 Assessin

13、g whether the 2017 Mw 5.4 Pohang earthquake in South Korea was an induced event K.-H.Kim et al.1010 ORGANIC CHEMISTRYA radical approach to the copper oxidative addition problem:Trifluoromethylation of bromoarenes C.Le et al.1014 PLANT SCIENCEFeedback regulation of COOLAIR expression controls seed do

14、rmancy and flowering time M.Chen and S.Penfield1017 EVOLUTIONPredator-driven natural selection on risk-taking behavior in anole lizards O.Lapiedra et al.1020 POLITICAL SCIENCEThe effect of partisanship and political advertising on close family ties M.K.Chen and R.RohlaHUMAN EVOLUTION1024 Ancient hum

15、an parallel lineages within North America contributed to a coastal expansion C.L.Scheib et al.1028 Ancient genomes from Iceland reveal the making of a human population S.S.Ebenesersdttir et al.PERSPECTIVE P.964ON THE COVERTiled confocal micros-copy image of a developing zebrafish embryo at single-ce

16、ll resolution,less than 1 day after fertiliza-tion.Single-cell RNA sequencing can be used to generate high-resolution maps of gene expression activity as embryos develop into fish and amphibians.See pages 967,979,980,and 981.Image:Frederique Ruf-Zamojski and Sean MegasonSCIENCE(ISSN 0036-8075)is published weekly on Friday,except last week in December,by the American Association for the Advancement of Science,1200 New York Avenue,NW,Washington,DC 20005.Periodicals mail postage(publication No.4844

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