1、宁夏医科大学学报45卷ResultsThere was no significant difference in age and sex between survival group and death group（P all0.05）.The APACHE-score，serum presepsin，and ESM-1 decreased gradually in the survival group，but not in thedeath group.The APACHE score in the survival group was statistically significant c
2、ompared with that in thedeath group on day 7 and day 14（P0.05）.Serum presepsin and ESM-1 levels in the death group were statisti-cally significant compared with those in the survival group on day 3，7，and 14（P all 927.5 pg mL-1and ESM-14.96 ng mL-1，the sensitivity of presepsin on day 1 andday 3 was d
3、ifferent from those of APACHE .There was a difference between ESM-1 and APACHE onday 1（P all0.05）.The specificity of presepsin differed from APACHE scores at day 3，7，and 14（P0.05），and ESM-1 was different from APACHEat each time point（P all0.05）.ConclusionSerum presepsindetection can improve the diag
4、nostic rate of ARDS caused by early sepsis，and ESM-1 detection can improvethe predictive ability of ARDS.Key words：sepsis；acute respiratory distress syndrome；soluble leukocyte differentiation antigen subtype 14；endothelial cell specific molecule-1；prognosis prognosis-1.567%），17.179%（95%CI：0.678%-36.
5、384%），2.940%（95%CI：2.470%-3.412%）and 0.426%（95%CI：0.175%-0.677%），respectively.And the strongest effect was achieved in lag01，lag06，lag07，and lag04，respectively.Seasonal stratification analysis showed that,except for the fact that the maximum effect values ofPM10were basically the same in the cold an
6、d warm seasons,the maximum effect values of PM2.5,NO2,and O3alloccured in the warm season,with the best lag days being lag1,lag7,and lag2,respectively.The season-stratifiedanalysis showed that the maximal effect of PM2.5，NO2and O3was higher in the cold season than in the warmseason，and the optimum l
7、ag condition were lag1，lag7 and lag2，respectively.Except that the maximum effect ofPM10was basically the same in cold and warm seasons.ConclusionThe increases in PM2.5，PM10，NO2and O3concentrations in Yinchuan city will increase the daily outpatient visits for respiratory diseases with a lag effect,w
8、ith PM10having the greatest impact on the daily outpatient volume.Key words：air pollution；respiratory disease；daily outpatient visits；time series analysis；generalized additivemodel（上接第 298 页）为顺应国际上的通行方法，更好地体现科研论文作者的分工协作关系，本刊决定在所发表的论文上可以注明通信作者。通信作者可以是第一作者，也可以是其他作者，但必须是论文负责者，对论文的科学性和结果、结论的可信性负主要责任，同时也是本刊和读者所联系的对象，本刊要求通信作者为研究生导师或科研课题的负责人。加注通信作者的主要内容包括作者姓名、单位、联系电话、电子信箱等信息。（本刊编辑部）关于加注“通信作者”的要求314