1、Designation:D3764151Standard Practice forValidation of the Performance of Process Stream AnalyzerSystems1This standard is issued under the fixed designation D3764;the number immediately following the designation indicates the year oforiginal adoption or,in the case of revision,the year of last revis
2、ion.A number in parentheses indicates the year of last reapproval.Asuperscript epsilon()indicates an editorial change since the last revision or reapproval.1NOTEEditorial changes made throughout in July 2015.INTRODUCTIONOperation of a process stream analyzer system typically involves four sequential
3、 activities.(1)Analyzer Calibration When an analyzer is initially installed,or after major maintenance hasbeen performed,diagnostic testing is performed to demonstrate that the analyzer meets themanufacturers specifications and historical performance standards.These diagnostic tests may requirethat
4、the analyzer be adjusted so as to provide predetermined output levels for certain referencematerials.(2a)Correlation for the Same MaterialOnce the diagnostic testing is completed,process stream samples are analyzed using the analyzer system.For application where the processanalyzer system results ar
5、e required to agree with results produced from an independent(primary)testmethod(PTM),a mathematical function is derived that relates the analyzer results to the primary testmethod results(PTMR).The application of this mathematical function to an analyzer result producesa predicted primary test meth
6、od result(PPTMR),for the same material.(2b)Correlation forMaterial including Effect fromAdditional Treatment to the MaterialThe PPTMR in(2a)can beused as an input to a mathematical model to predict the effect of an additive and/or a blendstock addedto a basestock material as measured by a PTM.(3)Pro
7、bationary ValidationAfter the correlation(s)relationship between the analyzer results and primary test method results has been established,aprobationary validation is performed using an independent but limited set of materials that were notpart of the correlation activity.This probationary validatio
8、n is intended to demonstrate that thePPTMRs agree with the PTMRs to within user-specified requirements for the analyzer systemapplication.(4)General and Continual ValidationAfter an adequate amount of PPTMRs andPTMRs have been accrued on materials that were not part of the correlation activity,a com
9、prehensivestatistical assessment is performed to demonstrate that the PPTMRs agree with the PTMRs to withinthe tolerances established from the correlation activities.Subsequent to a successful generalvalidation,quality assurance control chart monitoring of the differences between PPTMR and PTMRis co
10、nducted during normal operation of the process analyzer system to demonstrate that theagreement between the PPTMRs and PTMRs established in the General Validation is maintained.Thispractice deals with the third and fourth of these activities.“Correlation for material including effect from additional
11、 treatment to the material”as outlined inthis standard is intended primarily to be applied to biofuels where the biofuel material is added at aterminal or other facility and not included in the process stream material sampled by the analyzer atthe basestock manufacturing facility.The correlation sha
12、ll be specific for a constant percentageaddition of the biofuels material to the basestock for each model.This practice may not apply forphysical properties where the source material for the biofuel material or the denaturant/diluentmaterial used with the biofuel material can significantly affect th
13、e finished biofuels physical property.The user of the standard should investigate the effect of changes to biofuels material blend ratios,biofuels material source material,and blendstock material composition when using this practice.Limits to any of these may need to be applied when the correlation
14、is used.Copyright ASTM International,100 Barr Harbor Drive,PO Box C700,West Conshohocken,PA 19428-2959.United States1 1.Scope*1.1 This practice describes procedures and methodologiesbased on the statistical principles of Practice D6708 to validatewhether the degree of agreement between the results p
15、roducedby a total analyzer system(or its subsystem),versus the resultsproduced by an independent test method that purports tomeasure the same property,meets user-specified requirements.This is a performance-based validation,to be conducted usinga set of materials that are not used a priori in the de
16、velopmentof any correlation between the two measurement systems underinvestigation.A result from the independent test method isherein referred to as a Primary Test Method Result(PTMR).1.1.1 The degree of agreement described in 1.1 can be eitherfor the same materials,or,for materials including effect fromadditional treatment to the basestock material.NOTE1Subsection 1.1.1 refers to the application where PPTMR forthe same material can be used as an input to a mathematical model topredict the effec
