1、NEWSIN BRIEF124 News at a glanceIN DEPTH 128 YELLOW FEVER OUTBREAK HIGHLIGHTS VACCINE SHORTAGEA major resurgence of the disease strikes Angola By K.Kupferschmidt129 AN UNHAPPY PEACE DIVIDEND Colombia peace deal boosts growth,threatens ecosystems By L.Wade130 TALLYING THE LOSSES IN PALMYRAAfter Islam
2、ic State retreat,talk of restoration By Z.Zorich131 IRONIC CODA TO FRAUDULENT STUDYResearcher who exposed gay canvassing study fi nds same ef ect By J.Bohannon PERSPECTIVE P.147;REPORT P.220132 3D PRINTERS VULNERABLE TO SPYINGDesign information can be pilfered from printer sounds By M.HvistendahlFEA
3、TURES 134 ONLY THE STRONG SURVIVEScience in Putins Russia By R.Stone136 Global tensions rile experimental university By R.Stone8 APRIL 2016 VOLUME 352 ISSUE 6282CONTENTS144&187Regulatory RNAs control antibiotic resistance 8 APRIL 2016 VOL 352 ISSUE 6282 117SCIENCE sciencemag.orgINSIGHTSPERSPECTIVES
4、142 MOVING SUPERHYDROPHOBIC SURFACES TOWARD REAL-WORLD APPLICATIONSStandardized wear and durability testing is needed to advance the best materials By X.Tian et al.144(META-)GENOME MINING FORNEW RIBO-REGULATORSRNA regulatory elements arepotential antibiotic targets and synthetic biology building blo
5、cks By M.O.A.Sommer and B.Suess RESEARCH ARTICLE P.187145 HOW NEUTROPHILSPROMOTE METASTASISNeutrophils may be cellular targets for cancer therapy By T.Tting and K.E.de Visser METASTASIS SECTION P.162SPECIAL SECTIONMetastasisINTRODUCTION 162 An evolving storyNEWS164 Malignant messengers By J.KaiserPE
6、RSPECTIVE 167 A collective route to metastasis:Seeding by tumor cell clustersK.J.Cheung and A.J.EwaldREVIEWS 169 Metastasis as an evolutionary process S.Turajlic and C.Swanton 175 Hypoxic control of metastasis E.B.Rankin and A.J.GiacciaSEE ALSO EDITORIAL P.123 PERSPECTIVE P.145 RESEARCH ARTICLE P.18
7、9 REPORTS PP.227&242 PODCASTON THE COVERArtists interpretation of tumor cells in transit from the primary tumor(background)to the site of metastasis(foreground).After entering the vasculature(depicted as red snaking branches),circulating tumor cellsshown here in a much greater number than would occu
8、r in a cancer patienteventually exit at the metastatic site.Recent research on metastasis,a leading cause of cancer mortality,is highlighted in a special section beginning on page 162.Illustration:Valerie Altounian/Science138 POISED FOR LIFTOFFRussias space scientists plan an ambitious set of missio
9、ns By R.Stone140 OUT IN THE COLDRussias takeover of Crimea has isolated scientists in the strategic peninsula By R.Stone138Published by AAASon April 8,2016Downloaded from on April 8,2016Downloaded from 8 APRIL 2016 VOLUME 352 ISSUE 6282CONTENTS201Magnetic atoms playing under the lights 8 APRIL 2016
10、VOL 352 ISSUE 6282 119SCIENCE sciencemag.orgRESEARCHIN BRIEF 183 From Science and other journalsRESEARCH ARTICLES 187 TRANSCRIPTIONTerm-seq reveals abundant ribo-regulation of antibiotics resistance in bacteria D.Dar et al.RESEARCH ARTICLE SUMMARY;FOR FULL TEXT:dx.doi.org/10.1126/science.aad9822 PER
11、SPECTIVE P.144189 CANCER GENOMICSDissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq I.Tirosh et al.METASTASIS SECTION P.162197 QUANTUM HALL EFFECTThe half-fi lled Landau level:The case for Dirac composite fermions S.D.Geraedts et al.REPORTS 201 QUANTUM SIMULATIONExt
12、ended Bose-Hubbard models with ultracold magnetic atoms S.Baier et al.205 ELECTRONICSExploiting the colloidal nanocrystal library to construct electronic devices J.-H.Choi et al.208 ASTROCHEMISTRYRibose and related sugars from ultraviolet irradiation of interstellar ice analogs C.Meinert et al.213 Q
13、UANTUM CRITICALITYQuantum criticality with two length scales H.Shao et al.216 BRAIN CONNECTIVITYTask-free MRI predicts individual dif erences in brain activity during task performance I.Tavor et al.220 POLITICAL SCIENCEDurably reducing transphobia:A fi eld experiment on door-to-door canvassing D.Bro
14、ockman and J.Kalla NEWS STORY P.131;PERSPECTIVE P.147224 CLIMATE CHANGEObservational constraints on mixed-phase clouds imply higher climate sensitivity I.Tan et al.227 CANCER BIOLOGYMYC regulates the antitumor immune response through CD47 and PD-L1 S.C.Casey et al.METASTASIS SECTION P.162231 METABOL
15、ISMComplementation of mitochondrial electron transport chain by manipulation of the NAD+/NADH ratio D.V.Titov et al.235 HUMAN GENOMICSExcavating Neandertal and Denisovan DNA from the genomes of Melanesian individuals B.Vernot et al.239 BIOPHYSICSDirect observation of transition paths during the fold
16、ing of proteins and nucleic acids K.Neupane et al.PERSPECTIVE P.150242 CANCERSCS macrophages suppress melanoma by restricting tumor-derived vesicleB cell interactions F.Pucci et al.METASTASIS SECTION P.162SCIENCE(ISSN 0036-8075)is published weekly on Friday,except the last week in December,by the American Association for the Advancement of Science,1200 New York Avenue,NW,Washington,DC 20005.Periodicals mail postage(publication No.484460)paid at Washington,DC,and additional mailing of ces.Copyrig
