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1、384 22 APRIL 2016 VOL 352 ISSUE 6284sciencemag.org SCIENCE22 APRIL 2016 VOLUME 352 ISSUE 6284CONTENTS394Horned beetles put evolution to the test NEWSIN BRIEF388 News at a glanceIN DEPTH 391 REFUGEE CRISIS BRINGS NEW HEALTH CHALLENGESImported pathogens are a much bigger threat to migrants than they a

2、re to Europeans By K.Kupferschmidt392 HOW SIGN LANGUAGES EVOLVEYoung sign languages develop in predictable ways,of ering clues to language evolution By C.Matacic393 NO DEADLINE,FEWER REQUESTSNational Science Foundation trial spurs drop in proposals By E.Hand394 TEMPLETON GRANT FUNDS EVOLUTION RETHIN

3、K$8.7 million to test controversial ideas about how organisms infl uence their evolution By E.Pennisi395 THE TINIEST TITANFossil shows that even the youngest titanosaurs were ready to take on the world By P.Monahan REPORT P.450396 DATA CHECK:WHEN THE PAYOFF FOR ACADEMICS DROPS,COMMERCIALIZATION SUFF

4、ERSA change in Norways laws leads to sharp drop in the number of patents and startups by academics By J.MervisINSIGHTSPERSPECTIVES 408 WASTE NOT,WANT NOT,EMIT LESSReducing food waste in the supply chain and at home can help to reduce carbon emissions By J.Aschemann-Witzel410 ELECTRONS CATCH A TERAHE

5、RTZ WAVEFar-infrared fi elds control ultrashort electron pulses By C.Ropers RESEARCH ARTICLE P.429411 MINERAL CLUES TO PAST VOLCANISMA study of zircon minerals from around the world shows that volcanism is a key driver of long-term climate change By L.Kump REPORT P.444413 RISK LITERACY IN MEDICAL DE

6、CISION-MAKINGHow can we better represent the statistical structure of risk?By J.T.Operskalski and A.K.Barbey415 PAINTING MAGNETISM ON A CANVAS OF GRAPHENEHydrogen adatoms can give long-range magnetic order to graphene By S.M.Hollen and J.A.Gupta REPORT P.437FEATURES 398 MALARIA WARSCan malaria be el

7、iminated from the Mekong region before multiple-drug resistance makes it untreatable?By L.Roberts403 Skirmishing over the scope of the threatBy L.Roberts 404 Rubber workers on thefront linesBy L.Roberts405 THE UNLIKELY DIPLOMATMyaing Myaing Nyunt fl ed Myanmar in 1988;now she is back,forging allianc

8、es against malaria By L.Roberts407 THE VILLAGE RECRUITERIn tests of a controversial strategy,advance liaison to often-skeptical villagers is crucial By L.RobertsON THE COVERMigrant workers such as this man,one of nearly 50 workers employed at a farm in Palin,Cambodia,near the border with Thailand,ar

9、e at especially high risk of contracting malaria.Reaching them is one of many challenges facing an ambitious new ef ort to wipe out all malaria from the Greater Mekong subregion by 2030.See page 398.Photo:Jef rey Lau411&444397 CADAVER STUDY CHALLENGESBRAIN STIMULATION METHODSUnusual test of transcra

10、nial stimulation shows that little electrical current penetrates the skull By E.UnderwoodPublished by AAAS on April 21,2016http:/science.sciencemag.org/Downloaded from 22 APRIL 2016 VOL 352 ISSUE 6284 385SCIENCE sciencemag.org427How immune cells remember 410&429Controlling electron bursts Science St

11、af .386New Products.478Science Careers.480DEPARTMENTS387 EDITORIAL Due process in the Twitter ageBy Marcia McNutt486 WORKING LIFEGrowth can come in phasesBy He FuRESEARCHIN BRIEF 424 From Science and other journalsREVIEW427 INNATE IMMUNITYTrained immunity:A program of innate immune memory in health

12、and disease M.G.Netea et al.REVIEW SUMMARY;FOR FULL TEXT:dx.doi.org/10.1126/science.aaf1098RESEARCH ARTICLES 428 MICROTUBULESDetyrosinated microtubules buckle and bear load in contracting cardiomyocytes P.Robison et al.RESEARCH ARTICLE SUMMARY;FOR FULL TEXT:dx.doi.org/10.1126/science.aaf0659429 ULTR

13、AFAST OPTICSAll-optical control and metrology of electron pulses C.Kealhofer et al.PERSPECTIVE P.410REPORTS 433 ORGANIC CHEMISTRYCatalytic asymmetric addition of Grignard reagents to alkenyl-substituted aromatic N-heterocycles R.P.Jumde et al.437 MAGNETISMAtomic-scale control of graphene magnetism b

14、y using hydrogen atoms H.Gonzlez-Herrero et al.PERSPECTIVE P.415441 QUANTUM OPTICSBell correlations in a Bose-Einstein condensate R.Schmied et al.444 GEOLOGYContinental arc volcanism as the principal driver of icehouse-greenhouse variability N.R.McKenzie et al.PERSPECTIVE P.411448 BIOINORGANIC CHEMI

15、STRYLight-driven dinitrogen reduction catalyzed by a CdS:nitrogenase MoFe protein biohybrid K.A.Brown et al.450 PALEONTOLOGYPrecocity in a tiny titanosaur from the Cretaceous of Madagascar K.C.Rogers et al.NEWS STORY P.395;PODCAST453 CELL QUIESCENCERNA-binding proteins ZFP36L1 and ZFP36L2 promote ce

16、ll quiescence A.Galloway et al.459 IMMUNOLOGYHobit and Blimp1 instruct a universal transcriptional program of tissue residency in lymphocytes L.K.Mackay et al.463 INNATE IMMUNITYMx1 reveals innate pathways to antiviral resistance and lethal infl uenza disease P.S.Pillai et al.467 STRUCTURAL BIOLOGYThe 3.8 resolution cryo-EM structure of Zika virus D.Sirohi et al.470 EVOLUTIONARY GENETICSA beak size locus in Darwins fi nches facilitated character displacement during a drought S.Lamichhaney et al.

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