1、天 津 中 医 药 23年9月第40卷第9期Sep.23,40 9Changes in brain functional activity in migraine with anxiety and depression and the mechanism of acupuncture on itsregulation：a Meta鄄analysis of fMRI studiesCHEN Ying1，SUN Jingqing2，HONG Jiahui1，LIU Yuhan1，CHEN Qiuyi2，LIU Lu2（1.Beijing University of Chinese Medicine
2、，Beijing 100029，China；2.Beijing Key Laboratory of Acupuncture Neuromodulation，Department of Acupuncture and Moxibustion，Beijing Hospital of Traditional Chinese Medicine，Capital Medical University，Beijing100010，China）Abstract：Objective To evaluate the changes of brain function in migraine patients wi
3、th anxiety and depression and the effects ofacupuncture on brain function.Methods Domestic and foreign databases were searched from the establishment of each database to June2022.The literature on acupuncture treatment of migraine without aura using functional magnetic resonance imaging（fMRI）as theo
4、bservation index was systematically collected，and the clinical brain functional image studies of migraine patients with anxiety anddepression were screened out，and the brain functional image data of acupuncture treatment on migraine with anxiety and depression weresummarized.Image indicators were re
5、quired to include MNI（Montreal Neurological Institute）or Talairach spatial coordinates of activatedbrain regions，and voxel Meta鄄analysis was performed using Seed鄄based d Mapping（SDM）software.The characteristics of brain functionchange and the general rule of brain function change caused by acupunctu
6、re treatment of this disease were obtained.Results A total of186 literatures were retrieved，10 of which met the inclusion criteria，including 418 patients and 160 healthy controls.Voxel Meta鄄analysisof the 10 studies showed that the brain function of the left caudate nucleus in migraine with anxiety
7、and depression was more active thanthat in the healthy control，and the activity of the bilateral middle occipital gyrus and right suproccipital gyrus was less active than that inthe healthy control.Acupuncture decreased the brain function in the right middle frontal gyrus（P0.005）.Conclusion Acupunct
8、urecould reduce pain and anxiety鄄depression鄄related symptoms of migraine patients by increasing the functional activity of right middlefrontal gyrus.The changes of brain functional activity in comorbidities may be related to the chronic and aura symptoms of migraine.Keywords：migraine；comorbidity；anx
9、iety；depression；acupuncture；functional magnetic resonance imaging；systematic evaluation针灸和草药(英文)被Scopus数据库收录 消息 2023年3月，针灸和草（英文）（AHM）收到来自Scopus数据库遴选与审查委员会（CSAB）通知，经过严格评审，AHM被Scopus数据库正式收录！AHM在2019年12月入选中国科技期刊卓越行动计划高起点新刊项目，2022年5月被Directory ofOpen Access Jounals（DOAJ）数据库收录。2023年3月再度被世界一流学术研究数据库收录，标志着
10、该刊迈上一个新的台阶。在此，衷心感谢各位专家学者、读者、审稿人以及编委团队的大力支持与贡献。AHM将秉持初心，争创国际高水平学术期刊，继续为更多的专家学者和广大读者提供优质的出版服务！Scopus数据库由Elsevier于2004年11月推出。Scopus数据库的内容全面、学科广泛，覆盖自然科学、技术、工程、医学、社会科学、艺术与人文等学科，是目前全球规模最大的文摘和引文数据库。Scopus数据库由于其功能强大，已受到国内外学术界普遍关注，其数据在世界大学排行榜、中国高被引学者榜单、高校学科评估等方面得到广泛应用。AHM（ISSN2097-0226，CN12-1467/R）是国际化钻石OA期刊，受2019年度中国科技期刊卓越行动计划高起点新刊项目资助，已被DOAJ、Scopus两大重要数据库收录。期刊办刊宗旨为以循证医学研究为特色，刊载针灸和草药创新研究成果，促进学术交流，推动成果转化，服务中医药国际化发展。目前，AHM期刊文章涵盖多个热点研究方向，并受到国际学者广泛关注。未来，AHM将聚焦“讲好中医药科学故事”勇毅前行，推动中医药现代化、产业化，走向世界。1143
