1、Reduction in bile leaks following adult split liver transplant using afibrin-collagen sponge: A pilot study成人劈离式肝移植手术使用纤维蛋白胶原海绵后胆漏减少： 一项试点研究Back table preparation: liver cut surface after ex-vivo split procedure回表编制：劈离式手术拆分肝脏切表面Intra-operative view: blood rising from the liver cut surface after repe
2、rfusion术视图： 从肝移植手术再灌注切割表面血液上升Application of Tachosil on the cut surface: the surgeon presses on the sponge for 35 min with a wet swab在的切割面上的 Tachosil（可吸收性纤维胶原蛋白凝胶） 应用： 按 3-5 分钟，用湿棉棒海绵上的外科医生Bile leaks are a frequent complication of adult split liver transplantation. 胆汁泄漏是成人肝移植术常见的并发症。We compared surg
3、ical complications in patients who had the cut surface of the donor liver treated with a patch to those in whom the cut surface of the liver was treated with fibrin glue我们比较有术后并发症的捐助者肝脏表面治疗方法，那些人的肝脏的切割的面与纤维蛋白胶的修补程序。Material and methods:Two consecutive cohorts of 16 patients undergoing adult right lo
4、be split liver transplant were compared.。材料和方法： 两个连续组群 16 个接受成人右叶劈离式肝移植手术的患者进行了比较。 In the first cohort, the liver surface was treated with fibrin glue and in the second the liver surface was treated with TachoSil fibrinogen-thrombin-collagen patches. 在第一队列，肝表面使用纤维蛋白胶并在第二次肝脏表面处理 TachoSil 纤维蛋白原凝血酶胶原的修
5、补程序。 Post-operative complications were analyzed. 分析了术后并发症。Results:Bile leaks were significantly fewer among patients in whom the cut surface of the liver was treated with fibrin-collagen sponge compared to those where fibrin glue was used on the cut surface:1/16 (6.25%) vs. 7/16 (43.75%), respective
6、ly;p= 0.03. 结果：在人肝脏的切割的面使用纤维蛋白胶原海绵组患者胆漏发生明显较少于那些使用纤维蛋白胶组：1/16 (6.25%) vs. 7/16 (43.75%)分别 ； p = 0.03 There were some differences in biliary anastomotic techniques used in the two groups but 7/8 leaks (87.5%) arose from the cut surface, and only one was from the anastomosis.在两个组中使用的胆道吻合技术有一些差别，但 7/8
7、泄漏 (87.5%) 出现在切割面，并且只有一个是从吻合处。Conclusion:Using a fibrinogen-thrombin-collagen sponge patch may reduce bile leaks from the cut surface of the liver during adult right lobe split liver transplants. 结论： 使用纤维蛋白原凝血酶胶原海绵的修补术可以减少成人右叶劈裂式肝移植手术切割面的胆漏发生。 2009 Editrice Gastroenterologica Italiana S.r.l. Publish
8、ed by Elsevier Ltd. All rights reserved.In conclusion, our observation suggests that using a fibrinogen-thrombin-collagen sponge patch may reduce bile leaks from the cut surface of the liver during adult right lobe split liver transplants, and improve postoperative outcomes in these patients. 总之，我们的观察表明使用纤维蛋白原凝血酶胶原海绵修补程序可能会在成人右叶劈离式肝移植手术，期间从肝脏的切割面减少胆汁泄漏，改善这些患者的术后结果。
