1、天道酬勤海南医学院教案提要-海南医学院精品课程 海南医学院教案提要 20222023学年 第一学期 NO.1学科 medical microbiology 班级 undergraduate(04) 授 课 人 Huamin Wang 职 称 associate prof. 课题 anti-infectious immunity(bilingual) 学时120 minutes 授课时间 2022.10.11 教学方式 CAI 教学目的要求ObjectivesAims and ObjectivesTo understand how the body prevents entry of micro
2、-organisms. To understand the difference between innate and acquired immunity.The student will acquire knowledge of the theoretical basics of immunology, which allow him/her to: x comprehend：Acquired Immunity;Antibacterial responses;Anti- virus response.x understand：Innate Immunity;x recognize：Immun
3、e responses to fungi.2.内容提要、教学过程及学时分配Introduction 5 minutes Mechanisms of ImmunityInnate (Non-specific) Immunity 30 minutesNature barriers Natural immune cells Humoral soluable molecule Acquired Immunity 30 minutes Humoral Immune responseCellular Immune responseMucosal immune system,MIS 2 minutesAnt
4、ibacterial responses 25 minutesImmune responses for extracellular bacterial InfectionsImmune responses for intracellular bacterial InfectionsAnti- virus response 20 minutesNon antigen-specific Immune responseAntigen-specific Immune response Immune response to viral challengeImmune responses to fungi
5、 3 minutesSummary 5 minutes 3.重点、难点及解决方法key points: Acquired Immunity;Antibacterial responses;Anti- virus response.difficulty: Immune responses for intracellular bacterial Infections; Antigen-specific Immune response to virus.Methords to resolve:1.To review the knowledge which learned in Immonology2
6、. Using images and animations help studengs know the mechanisms of immnunity.3. bilingua注：每次授课需用新教案；教研室于开课前检查，课完后统一上交。4.使用教具(写出主要内容的名称备查)PPT file:Anti-infectious Immunity5.本课题方面的新进展 There are many progesses in immunology. Such as following:1.Multiple Roles of Antimicrobial Defensins, Cathelicidins,
7、and Eosinophil-Derived Neurotoxin in Host Defense.2.Starting at the Beginning: New Perspectives on the Biology of Mucosal T Cells.3.Immunological Memory to Viral Infections.4.Chemokines in Innate and Adaptive Host Defense: Basic Chemokinese Grammar for Immune Cells.6.板书的专用外语词汇本科授课每学时至少3个Anti-infecti
8、ous Immunity Innate (Non-specific) Immunity Nature barriers Nature immune cells Humoral soluble molecule Phagocyte NK cell Mast cell Phagocytosis Opsonization Inflammatory response Complement Humoral Immune response Cellular Immune responseMucosal immune system(MIS) ADCC7.参考书籍正任主编医学微生物学第六版，人民卫生出版社闻玉
9、梅主编现代微生物学Microbiology (fifth edition) (Lansing M.Prescott,etc. International Edition,ISBN0-07-112259-1)Medical microbiology (third edition) (Murry,etc. Mosby,ISBN0-8151-9035-2)Kuby Immunology (fouth edition) (Goldby,Richard, ISBN 0-7167-3331-5)8.思考题或/及作业1机体如何防御微生物感染？2机体如何记住原先感染的微生物，并在其再次感染时发挥更快和更有效的
10、免疫应答？3机体的天然屏障有那些？4抗胞外菌免疫和抗胞内菌免疫有什么区别？5抗病毒免疫的特点是什么？6再次免疫应答主要由什么细胞发挥作用，有何特点？9.课后记及改良意见10.备注海南医学院教案提要20222023 学年 第一学期 NO.2学科 医学微生物学 班级 06本护、中 、中西 授 课 人 王华民 职 称 教授 课题 肝炎病毒HBV 学时 3学时 授课时间 2022.12.1920 教学方式 CAI双语1.教学目的要求 掌握：乙型肝炎病毒的病毒学特征、致病性与免疫性。 熟悉：肝炎病毒的概念，人类肝炎病毒的型别及其主要特征；乙型肝炎病毒病毒学检查法及人 工自动免疫的应用。 General
11、Goal: To know the major causes of this disease, how they are transmitted, and the major manifestations of the disease.Specific Educational Objectives: The student should be able to:1.describe the common causes of blood-borne hepatitis and how they are transmitted. know the common means of transmissi
12、on and what people groups are more likely to be infected.2. describe the major manifestations of this disease. Know what human cells the viruses replicate in.3. diagnose (infected or not) and stage (acute, window period, chronic, infectious, etc.) hepatitis B via serological testing. Therefore you s
13、hould know the difference between a serological test for an antigen (HBsAg) and for an antibody (antiHBs).4define the difference between acute infections, chronic infections, fulminant hepatitis, which hepatitis virus infections are more likely to result in hepatocellular carcinoma.5describe how you
14、 can prevent hepatitis B infections.2.内容提要、教学过程及学时分配 1、组织教学并导入新课 5min 2、肝炎病毒的概念(General Concepts、Definitions for Hepatitises) 10min 3、人类肝炎的型别及主要特征 (Introduce to 6 types of hepatitis viruses & Viral Hepatitis) 10min 4、乙肝病毒Hepatitis B virus 生物学特性(Properties of HBV) 25 min 致病性与免疫性(Transmission、Pathogen
15、esis & Immunology) 40 min 微生物学检查法(Laboratory_Diagnosis ) 15 min 防治原那么Treament & Prevention 10 min 总结summary 5 min3.重点、难点及解决方法 重点：乙型肝炎病毒的病毒学特征、致病性与免疫性。 结合图表反复讲 难点：乙型肝炎病毒的基因结构、致病性与免疫性、乙肝两对半的分析。 结合图表通俗讲注：每次授课需用新教案；教研室于开课前检查，课完后统一上交。4.使用教具(写出主要内容的名称备查)CAI课件自制：肝炎病毒HBV英语5.本课题方面的新进展 变异株的研究、HBV受体研究、乙肝防治：乙肝病毒DNA聚合酶活性区发生变异与拉米夫定。人体基因多态性与HBV/HCV感染间关系：宿主在乙型肝炎病毒hepatitis B virus，HBV和丙型肝炎病毒hepatitis C virus，HCV感染后不同的临床开展过程，除了与病毒本身的因素有关外，更重要的是由于不同个体对HBV/H
