1、Designation:D648518Standard Guide forRisk Characterization of Acute and Irritant Effects of Short-Term Exposure to Volatile Organic Chemicals Emitted fromBedding Sets1This standard is issued under the fixed designation D6485;the number immediately following the designation indicates the year oforigi
2、nal adoption or,in the case of revision,the year of last revision.A number in parentheses indicates the year of last reapproval.Asuperscript epsilon()indicates an editorial change since the last revision or reapproval.1.Scope1.1 This guide describes procedures for conducting riskcharacterization of
3、exposure to volatile organic chemicals(VOCs)emitted from bedding sets or an ensemble of a mattressand supporting box spring.1.2 This guide is for risk characterization of short-termexposures to a new bedding set brought into a residentialindoor environment.The risk characterization considerationspre
4、sented in this guide are applicable to both the generalpopulation and sensitive subgroups,such as convalescingadults.1.3 The risk characterization addressed in this guide islimited to acute health and irritation effects resulting fromshort-term exposure to VOCs in indoor air.Although certainprocedur
5、es described in this guide may be applicable toassessing long-term exposure,the guide is not intended toaddress cancer and other chronic health effects.1.4 VOC emissions from bedding sets,as in the case ofother household furnishings,usually are highest when theproducts are new.A used bedding set may
6、 also emit VOCs,either from the original materials or as a result of its use.Theprocedures presented in this guide also are applicable to usedbedding sets.1.5 Risk characterization procedures described in this guideshould be carried out under the supervision of a qualifiedtoxicologist or risk assess
7、ment specialist,or both.1.6 The values stated in SI units are to be regarded asstandard.No other units of measurement are included in thisstandard.1.7 This standard does not purport to address all of thesafety concerns,if any,associated with its use.It is theresponsibility of the user of this standa
8、rd to establish appro-priate safety,health,and environmental practices and deter-mine the applicability of regulatory limitations prior to use.1.8 This international standard was developed in accor-dance with internationally recognized principles on standard-ization established in the Decision on Pr
9、inciples for theDevelopment of International Standards,Guides and Recom-mendations issued by the World Trade Organization TechnicalBarriers to Trade(TBT)Committee.2.Referenced Documents2.1 ASTM Standards:2D1356 Terminology Relating to Sampling and Analysis ofAtmospheresD6177 Practice for Determining
10、 Emission Profiles of Vola-tile Organic Chemicals Emitted from Bedding SetsD6178 Practice for Estimation of Short-term Inhalation Ex-posure to Volatile Organic Chemicals Emitted from Bed-ding SetsE609 Terminology Relating to PesticidesE943 Terminology Relating to Biological Effects and Envi-ronmenta
11、l Fate2.2 Government Standards:3EPA 600/R 92/047 Reference Guide to Odor Thresholds forHazardous Air Pollutants Listed in the Clean Air ActAmendments of 199029 CFR 1910 Occupational Safety and Health Standards3.Terminology3.1 DefinitionsFor definitions of terms used in this guide,refer to Terminolog
12、y D1356.1This guide is under the jurisdiction of ASTM Committee D22 on Air Qualityand is the direct responsibility of Subcommittee D22.05 on Indoor Air.Current edition approved April 15,2018.Published May 2018.Originallyapproved in 1999.Last previous edition approved in 2011 as D6485 11.DOI:10.1520/
13、D6485-18.2For referenced ASTM standards,visit the ASTM website,www.astm.org,orcontact ASTM Customer Service at serviceastm.org.For Annual Book of ASTMStandards volume information,refer to the standards Document Summary page onthe ASTM website.3Available from U.S.Government Printing Office,Superinten
14、dent ofDocuments,732 N.Capitol St.,NW,Washington,DC 20401-0001,http:/www.access.gpo.gov.Copyright ASTM International,100 Barr Harbor Drive,PO Box C700,West Conshohocken,PA 19428-2959.United StatesThis international standard was developed in accordance with internationally recognized principles on st
15、andardization established in the Decision on Principles for theDevelopment of International Standards,Guides and Recommendations issued by the World Trade Organization Technical Barriers to Trade(TBT)Committee.1 3.2 Definitions of Terms Specific to This Standard:3.2.1 acute exposure guideline levels
16、(AEGLs),nrepresentshort-term threshold or ceiling exposure values intended for theprotection of the general public,including susceptible orsensitive individuals,but not hypersusceptible or hypersensi-tive individuals(1).43.2.1.1 DiscussionAEGLs are for once-in-a-lifetime ex-posure due to accidental releases.Three AEGLs,each repre-senting distinct biological endpoints(sensory irritation ornotable discomfort,irreversible or serious effect,and life-threatening effects or death)for four different ex
