1、Designation:E288212Standard Guide forAnalysis of Clandestine Drug Laboratory Evidence1This standard is issued under the fixed designation E2882;the number immediately following the designation indicates the year oforiginal adoption or,in the case of revision,the year of last revision.A number in par
2、entheses indicates the year of last reapproval.Asuperscript epsilon()indicates an editorial change since the last revision or reapproval.1.Scope1.1 This guide is intended to be used in conjunction with thegeneral requirements for the analysis of seized drugs(PracticesE2326,E2327,E2329,and E2549;Guid
3、es E2548 and E2329).This guide provides guidance on the chemical analysis of itemsand samples related to suspected clandestine drug laboratories.It does not address scene attendance or scene processing.Thisdocument provides general guidance for the analysis of clan-destine laboratory evidence and is
4、 not a substitute for detailedand validated laboratory policies and technical procedures.1.2 This guide does not replace knowledge,skill,ability,experience,education,or training and should be used inconjunction with professional judgment.2.Referenced Documents2.1 ASTM Standards:2D6161 Terminology Us
5、ed for Microfiltration,Ultrafiltration,Nanofiltration and Reverse Osmosis Membrane ProcessesE1605 Terminology Relating to Lead in BuildingsE2326 Practice for Education and Training of Seized-DrugAnalystsE2327 Practice for Quality Assurance of Laboratories Per-forming Seized-Drug AnalysisE2329 Practi
6、ce for Identification of Seized DrugsE2363 Terminology Relating to Process Analytical Technol-ogy in the Pharmaceutical IndustryE2548 Guide for Sampling Seized Drugs for Qualitative andQuantitative AnalysisE2549 Practice for Validation of Seized-Drug AnalyticalMethodsF2725 Guide for European Unions
7、Registration,Evaluation,and Authorization of Chemicals(REACH)Supply ChainInformation Exchange3.Terminology3.1 Definitions of Terms Specific to This Standard:3.1.1 capacitythe amount of finished product that couldbe produced,either in one batch or over a defined period oftime,and given a set list of
8、variables.SWGDRUG33.1.2 catalysta substance whose presence initiates orchanges the rate of a chemical reaction,but does not itself enterinto the reaction.D61613.1.3 finished producta manufactured product ready foruse.SWGDRUG33.1.4 intermediateubstance that is manufactured for andconsumed in or used
9、for chemical processing to be transformedinto another substance.F27253.1.5 reagenta chemical used to react with anotherchemical,often to confirm or deny the presence of the secondchemical.E16053.1.6 yield,expectedthe quantity of material or the per-centage of theoretical yield anticipated at any app
10、ropriatephase of production based on previous laboratory,pilot scale,or manufacturing data.E23633.1.7 yield,theoreticalthe quantity that would be pro-duced at any appropriate phase of production based upon thequantity of material to be used,in the absence of any loss orerror in actual production.E23
11、634.Significance and Use4.1 An understanding of clandestine laboratory syntheticroutes and the techniques used in the analysis of relatedsamples is considered to be fundamental to the interpretationand reporting of results.This understanding assures that resultsand conclusions from methods are relia
12、ble and analyticalschemes are fit for purpose.4.2 The qualitative and quantitative analyses of clandestinelaboratory evidence can require different approaches relative toroutine seized drug analyses.Analysts shall understand thelimitations of the procedures used in their qualitative andquantitative
13、analyses.These include such factors as methodselectivity,uncertainty,and the basis for inferences from asample(s)to a population.4.3 Laboratory management shall ensure that clandestinelaboratory synthesis and analysis training be provided through1This guide is under the jurisdiction of ASTM Committe
14、e E30 on ForensicSciences and is the direct responsibility of Subcommittee E30.01 on Criminalistics.Current edition approved Aug.1,2012.Published September 2012.DOI:10.1520/E2882-12.2For referenced ASTM standards,visit the ASTM website,www.astm.org,orcontact ASTM Customer Service at serviceastm.org.
15、For Annual Book of ASTMStandards volume information,refer to the standards Document Summary page onthe ASTM website.3Available from the Scientific Working Group for the Analysis of Seized Drugs,http:/www.swgdrug.org.Copyright ASTM International,100 Barr Harbor Drive,PO Box C700,West Conshohocken,PA
16、19428-2959.United States1 relevant procedures,literature,and practical experience.Prac-tical experience typically includes production,sampling andanalysis of clandestine laboratory training samples.4.4 Laboratory management shall ensure that chemicalsafety and hygiene plans address and mitigate hazards associ-ated with clandestine laboratory evidence.4.5 Laboratory management shall consider customer/localrequirements which influence the application of these recom-mendations.5.Safety5.1 This guid
